3-Oxooleanolic Acid: Advanced Triterpenoid for Biomedical Research
1. Molecular Identity
- Chemical Name: 3-Oxoolean-12-en-28-oic acid
- CAS Number: 17990-42-0
- Source: Derivative of oleanolic acid, found in various plant species or synthetically produced
2. Biochemical Significance
3-Oxooleanolic acid is a triterpenoid compound derived from oleanolic acid. Its unique molecular structure, featuring a ketone group at the C-3 position, contributes to its diverse biological activities, making it a compound of significant interest in natural product research and potential therapeutic applications.
3. Key Properties
- Anti-inflammatory: Demonstrates potential in modulating inflammatory responses
- Antioxidant: Exhibits free radical scavenging capabilities
- Anticancer Potential: Shows promise in various cancer models
- Hepatoprotective: Indicates liver-protecting properties
4. Potential Research Applications
- Cancer research and drug development
- Inflammatory disorder studies
- Liver disease investigations
- Antioxidant and free radical research
5. Current Research Focus
Ongoing studies are investigating 3-Oxooleanolic acid’s effects on:
- Various cancer types and mechanisms of action
- Inflammatory signaling pathways
- Liver fibrosis and hepatotoxicity
- Oxidative stress-induced cellular damage
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing bioavailability and solubility
- Developing targeted delivery systems for improved efficacy
- Creating semi-synthetic derivatives with optimized properties
7. Regulatory Considerations
As a research compound, 3-Oxooleanolic acid (CAS 17990-42-0) is primarily used in preclinical studies. Its development for therapeutic applications would require extensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced studies on the molecular mechanisms of 3-Oxooleanolic acid’s biological activities
- Exploration of its potential in combination therapies
- Investigation of structure-activity relationships for optimized derivatives
9. Collaborative Opportunities
We invite cancer researchers, pharmacologists, natural product scientists, and academic institutions to explore the research potential of 3-Oxooleanolic acid. For inquiries, collaborations, or to discuss how 3-Oxooleanolic acid can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biomedical research with 3-Oxooleanolic acid – a promising triterpenoid at the intersection of natural product chemistry and innovative therapeutic strategies.