5-Hydroxytryptophan (5-HTP): Amino Acid Derivative for Neurocosmetic & Anti-Stress Skincare

Molecular Identity

• Chemical Name (INCI): 5-Hydroxytryptophan
• Molecular Formula: C₁₁H₁₂N₂O₃
• Source: Extracted from Griffonia simplicifolia seeds or synthesized to high purity

Function & Applications

5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid intermediate between tryptophan and serotonin. In cosmetic science, it is explored for use in **neurocosmetic formulations**, supporting skin well-being and stress relief. It also contributes to hydration and comfort in daily-use skincare:

• Neuro-soothing: Supports skin’s relaxation pathways via topical serotonin-related mechanisms
• Moisture Modulation: Improves skin comfort and reduces dryness-related tension
• Skin Wellness: Enhances mood-related perception of cosmetic use
• Prebiotic Synergy: Can support microbiome-friendly and mind-skin formulas

Recommended for: anti-stress creams, mood-enhancing emulsions, hydration serums, and scalp care. Available in bulk quantities for industrial-scale formulation.

Typical Usage & Dosage

• Neurocosmetic skincare: 0.05–0.2%
• Soothing or hydration-focused formulas: 0.1–0.3%
• Scalp calming systems: up to 0.5%

Water-soluble. Add during aqueous or final phase. pH range: 4.5–7. Avoid high heat (>40°C) during addition.

Technical Highlights

• Purity ≥ 99% (HPLC)
• Appearance: Off-white to light gray powder
• Odorless, vegan, non-GMO
• Low interaction with color and fragrance systems

Each batch is shipped with full documentation: COA, HPLC, MSDS, microbial and heavy metal testing, residual solvents, and stability data.

Regulatory & Compliance Info

• INCI: 5-Hydroxytryptophan
• CAS Number: 4350-09-8
• Cosmetic-grade, technical-grade upon request
• REACH status: available on request
• Compliant with EU/US ingredient regulations (non-ingestible use only)

Why Choose Us – Bulk Ingredient Supply

• High-purity 5-HTP optimized for topical cosmetic applications
• Bulk inventory available in EU warehouse with fast dispatch
• Technical documentation included for regulatory teams and R&D labs
• Flexible batch sizes for pilot or production scale
• Secure sourcing for long-term formulation needs
• Tiered B2B pricing for manufacturers, labs, and contract developers

Contact us for sample requests, bulk pricing, or full specification files for 5-HTP.