Ammonium Glycyrrhizate CAS 53956-04-0 Bulk Supplier | High-Purity Licorice-Derived Ingredient

Ammonium Glycyrrhizate (CAS 53956-04-0) is a high-purity salt of glycyrrhizic acid, a natural triterpenoid saponin extracted from the roots of Glycyrrhiza glabra (licorice). Supplied as a yellowish-brown fine powder with ≥75% purity (HPLC), it is widely used in cosmetics, personal care, and pharmaceutical formulations for its soothing and harmonizing functional profile.

Product Description

This ingredient is valued for its amphiphilic molecular structure, which enhances solubility and stability in both aqueous and emulsion systems. Ammonium Glycyrrhizate offers natural foaming, emulsifying, and anti-irritant functions, making it ideal for sensitive skin formulations. Each batch is analytically confirmed by IR and TLC, with strict impurity and heavy metal limits verified via ICP-MS. Its mild sensory properties and botanical origin make it a preferred ingredient in natural and dermatologically tested formulations.

Technical Properties

• CAS Number: 53956-04-0
• Molecular Formula: C₄₂H₆₁O₁₆NH₄
• Molecular Weight: 839.97 g/mol
• Appearance: Fine powder
• Color: Yellowish-brown
• Purity: ≥ 75.0% (HPLC)
• Loss on Drying: ≤ 6.0%
• Sulfated Ash: ≤ 2.0%
• pH (1% solution): 4.0 – 4.4
• Heavy Metals: ≤ 10 ppm (Pb ≤ 2 ppm, As ≤ 1 ppm, Hg ≤ 0.1 ppm, Cd ≤ 1 ppm)

Applications & Industries

Ammonium Glycyrrhizate serves as a multifunctional licorice-derived active for cosmetics, dermocosmetics, and pharmaceutical formulations. It combines soothing efficacy, formulation compatibility, and clean-label positioning.

• Cosmetics & Skincare: Commonly incorporated into lotions, creams, and toners designed for sensitive or reactive skin. It helps balance sebum production and provides calming effects, supporting barrier repair and skin comfort.
• Hair Care: Used in scalp-care and anti-dandruff formulations for its natural soothing and anti-irritant benefits. It enhances tolerance of surfactant systems and promotes a balanced scalp environment.
• Pharmaceuticals: Applied as a functional excipient in topical products and oral care formulations. Its stabilizing nature improves formulation homogeneity and supports product shelf-life.
• Personal Hygiene & Oral Care: Incorporated into toothpastes and mouth rinses for its sweet, mild flavor and bioactive profile. It provides additional functional value without synthetic sweeteners or harsh additives.

Key Advantages

High-quality licorice-derived active: Sourced from Glycyrrhiza glabra, this ingredient preserves the natural triterpenoid structure responsible for its soothing and balancing properties. The botanical sourcing supports eco-conscious and clean beauty product concepts.

Excellent compatibility and stability: The ammonium salt form enhances solubility and maintains functional performance in both water-based and emulsion systems. It performs consistently across pH 4–6, allowing broad formulation flexibility.

Strict quality assurance and analytical control: Each production lot is validated via HPLC, IR, and TLC with ICP-MS screening for heavy metals. Low ash and moisture levels ensure high stability and batch-to-batch reproducibility.

Comprehensive regulatory documentation: Delivered with COA, MSDS, and technical data sheets to support EU Cosmetic Regulation compliance and international B2B product registration.

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