Diacetyl Boldine CAS 72584-75-9 Bulk Supplier | High-Purity Cosmetic Alkaloid

Diacetyl Boldine (CAS 72584-75-9) is a semi-synthetic derivative of boldine, used primarily in cosmetic and dermatological applications. Supplied as a white fine powder with ≥95.0% purity (HPLC), it is valued for its stability, well-defined analytical profile, and compatibility with premium skincare and active cosmetic formulations.

Product Description

Diacetyl Boldine is a high-purity cosmetic-grade alkaloid recognized for its clean analytical characteristics and suitability for advanced topical formulations. Each batch is verified for purity, identification (TLC & NMR), moisture content, ash, solvent residues, heavy metals, and microbiological safety. Its fine powder form, characteristic appearance, and controlled impurity profile support high-performance skincare and functional ingredient development.

Technical Properties

• CAS Number: 72584-75-9
• Molecular Formula: C₂₃H₂₅NO₆
• Molecular Weight: 411.40 g/mol
• Appearance: Fine powder
• Color: White
• Identification: Conforms (TLC & NMR)
• Purity: ≥ 95.0% (HPLC)
• Sulfated Ash: ≤ 2.0%
• Loss on Drying: ≤ 5.0%
• Solvent Residues: USP <467> (GC)
• Heavy Metals: ≤ 10 ppm
• Lead: ≤ 2 ppm
• Arsenic: ≤ 1 ppm
• Mercury: ≤ 0.1 ppm
• Cadmium: ≤ 1 ppm
• TPC: Not more than 10³ CFU/g
• TYMC: Not more than 10² CFU/g
• E. coli: Absent
• Salmonella: Absent
• Staphylococcus aureus: Absent

Applications & Industries

Diacetyl Boldine bulk powder is a premium cosmetic alkaloid tailored for skincare and dermatological formulations.

• Cosmetics & Personal Care: Applied in brightening, toning, and advanced skincare formulations due to its stable profile and compatibility with active complexes.
• Dermatological Preparations: Utilized in R&D and high-value topical systems requiring reliable, well-characterized alkaloids.
• Functional Ingredient Systems: Acts as a supportive compound in formulations emphasizing skin vitality and specialized cosmetic positioning.
• Pharmaceutical & Research Use: Suitable as an analytical reference material and for studies involving boldine-derived structures.
• Innovative Cosmetic Concepts: Provides formulation flexibility for premium beauty products requiring distinct, high-quality actives.

Key Advantages

High-purity cosmetic alkaloid: With ≥95.0% purity (HPLC) and controlled impurity limits, Diacetyl Boldine ensures consistent performance in premium skincare and cosmetic applications.

Defined analytical characteristics: Verified by TLC, NMR, and HPLC, with precise limits for moisture, ash, solvent residues, and heavy metals.

Formulation-friendly properties: Fine white powder form supports easy incorporation into emulsions, serums, creams, and advanced delivery systems.

Clean microbiological profile: Absence of E. coli, Salmonella, and S. aureus ensures suitability for regulated cosmetic and dermatological environments.

Documentation included: Supplied with COA, MSDS, and complete specification data to support QA, R&D, and regulatory workflows.

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