Dihydroartemisinin: Advanced Cosmetic Active for Tone Regulation, Oxidative Stability and Skin Brightening Support

Molecular Identity

• INCI Name: Dihydroartemisinin
• Molecular Formula: C₁₅H₂₄O₅
• Source: Semi-synthetic derivative of Artemisia annua, processed for cosmetic-grade use

Functional Use in Cosmetics

Dihydroartemisinin is a sesquiterpene lactone structurally related to artemisinin, offering benefits in cosmetic formulations targeting uneven skin tone, oxidative degradation control, and clarity enhancement. Its high oxygen-bearing structure allows it to support product stability and skin luminosity without causing irritation.

• Skin Clarity: Applied in brightening blends to support even tone and visible radiance
• Formulation Stability: Contributes to oxidative balance in emulsions and active-loaded systems
• Low Irritation Profile: Suitable for formulations aimed at sensitive or post-stress skin
• Innovative Appeal: Plant-origin molecule with high purity and performance focus

Integrated into modern emulsions, pigment-control creams, or antioxidant-rich daily care products. Supplied in bulk quantities for regulated B2B formulation use.

Typical Usage Guidelines

• Skin tone correction formulas: 0.05–0.3%
• Antioxidant emulsions and gels: 0.05–0.2%
• Pre/post-exposure care: 0.05–0.1%

Dihydroartemisinin is moderately soluble in ethanol and glycols; should be protected from strong light and high temperatures. Add during the final mixing phase under controlled conditions. Optimal pH: 5.0–6.5.

Technical Specifications

• Purity: ≥ 98% (HPLC)
• Appearance: White to slightly off-white crystalline powder
• Odor: Characteristic, mild
• Solubility: Soluble in ethanol, DMSO, PEGs

Each batch is supplied with COA, MSDS, HPLC data, residual solvent profile, microbial limits, and heavy metal analysis.

Regulatory Status

• INCI: Dihydroartemisinin
• CAS Number: 71939-50-9
• Intended for cosmetic use only
• Complies with EU Regulation EC No. 1223/2009
• REACH documentation available on request

B2B Supply & Technical Support

• Available from EU warehouse with short lead times
• Packaging options from R&D to full-scale production
• Stable and traceable sourcing for regulatory compliance
• Formulation guidance for tone-evening and oxidative-stability applications
• B2B pricing options for contract manufacturers and OEM partners

Contact us for a technical dossier, bulk pricing, or to request a formulation sample of Dihydroartemisinin.