Glycyrrhetinic Acid: Botanical Active for Sensitive Skin Relief and Anti-Redness Care

Ingredient Overview

Glycyrrhetinic Acid is a triterpenoid compound obtained through hydrolysis of glycyrrhizic acid found in licorice root (Glycyrrhiza glabra). Known for its calming and skin-conditioning benefits, it is commonly applied in soothing formulations for sensitive or redness-prone skin types.

INCI & Source

• INCI Name: Glycyrrhetinic Acid
• Molecular Formula: C₃₀H₄₆O₄
• Botanical Origin: Derived from licorice root extract

Why Use Glycyrrhetinic Acid?

• Soothing Function: Commonly used in skincare to reduce visible redness and discomfort
• Barrier Support: Contributes to improved skin resilience in compromised or irritated skin
• Ideal for Sensitive Formulas: Non-sensitizing and well-tolerated by delicate skin
• Oil-Soluble: Easily incorporated into oil-phase or emulsified systems

Application Areas

This active is frequently used in:

• Calming serums and creams
• After-sun or post-peel skincare
• Barrier creams for sensitive or reactive skin
• Soothing scalp treatments

Recommended Usage

• Topical emulsions or gels: 0.05–0.3%
• Scalp serums or rinse-off treatments: 0.02–0.2%
• Skin recovery formulas: 0.1–0.4%

Should be dissolved in ethanol, glycols or solubilizers; process at ≤ 60 °C. pH range: 5.0–7.0.

Physical & Technical Profile

• Appearance: White to off-white fine powder
• Purity: ≥ 98% (HPLC)
• Solubility: Soluble in ethanol, DMSO, PEGs; insoluble in water
• Odor: Neutral

Standard documentation includes: COA, MSDS, HPLC profile, microbiological testing, residual solvents and heavy metals data.

Compliance & Safety

• CAS Number: 471-53-4
• Topical use only in cosmetic applications
• EU Cosmetic Regulation compliant (EC No. 1223/2009)
• REACH status: Available upon request

Commercial Availability & B2B Advantages

• Bulk inventory available from EU warehouse
• Flexible packaging for R&D, pilot and industrial volumes
• Tailored B2B pricing for formulation partners and manufacturers
• Technical support for integration in sensitive skin formulations

Contact us to request documentation, samples or pricing for Glycyrrhetinic Acid.