Hyodeoxycholic Acid CAS 83-49-8 Bulk Supplier | High-Purity Bile Acid Derivative

Hyodeoxycholic Acid (CAS 83-49-8) is a secondary bile acid naturally derived from animal bile or synthesized for pharmaceutical applications. Supplied as a fine white powder with ≥98% purity (HPLC), it is known for its role in lipid metabolism, cholesterol regulation, and liver protection studies, making it a vital compound for pharmaceutical and biochemical industries.

Product Description

This compound exhibits strong chemical stability and a well-defined crystalline structure with a melting point between 190°C and 201°C. Each batch of Hyodeoxycholic Acid undergoes analytical testing by HPLC for purity, polarimetry for optical rotation, and in-house gravimetric controls for ash and moisture content. The result is a pharmaceutical-grade ingredient suitable for advanced formulation and analytical research.

Technical Properties

• CAS Number: 83-49-8
• Molecular Formula: C₂₄H₄₀O₄
• Molecular Weight: 392.57 g/mol
• Appearance: Fine white powder
• Purity: ≥ 98.0% (HPLC)
• Sulfated Ash: ≤ 0.2%
• Loss on Drying: ≤ 1.0%
• Optical Rotation: +6.5° to +9.0°
• Melting Point: 190–201°C
• Identification: Conforms (NMR)

Applications & Industries

Hyodeoxycholic Acid is a multifunctional bile acid widely utilized in pharmaceutical and biochemical applications due to its stable chemical behavior and physiological relevance.

• Pharmaceutical Industry: Applied as a biochemical intermediate in cholesterol-lowering drug synthesis and hepatoprotective formulations. Its structural similarity to endogenous bile acids makes it suitable for pharmacological modeling and metabolic studies.
• Biochemical Research: Used as a reference compound for bile acid metabolism and transport analysis. Researchers employ it to investigate intestinal absorption mechanisms and liver detoxification pathways in preclinical studies.
• Nutraceuticals & Functional Health: Emerging as a functional ingredient in advanced formulations targeting lipid metabolism and digestive balance. Its bioidentical structure allows incorporation into next-generation nutraceutical concepts.
• Analytical Chemistry: Serves as a calibration and analytical standard for chromatographic studies. Its well-defined purity and optical rotation range provide reproducible benchmarks for quality control laboratories.

Key Advantages

Pharmaceutical-grade quality control: Every batch of Hyodeoxycholic Acid is tested using validated HPLC and NMR methods to ensure consistency and reliability. Strict control over purity, optical rotation, and melting point ensures compliance with pharmaceutical quality standards.

Consistent supply and technical traceability: Sourced and produced under ISO-aligned procedures, guaranteeing reliable batch documentation and reproducible performance across different production cycles. This ensures seamless integration into regulated manufacturing workflows.

Versatile biochemical applicability: The compound’s compatibility with various organic solvents and stability under processing conditions make it suitable for both bench-scale and industrial synthesis. It maintains performance integrity across diverse formulation environments.

Comprehensive documentation support: Delivered with a detailed Certificate of Analysis (COA), MSDS, and analytical reports to support regulatory submissions, research verification, and international distribution.

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