7-Dehydrocholesterol CAS 434-16-2

2801100

Synonyms: Cholesta-5,7-dien-3β-ol

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Cat. No. NST-10-88
CAS 434-16-2
Assay 95% (HPLC)
Appearance White Powder
Molecular formula C27H44O
Molecular weight 384,65
Storage +2 … +8 °C

Certificate of analysis available by request to [email protected]

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Description

7-Dehydrocholesterol: Crucial Precursor for Advanced Vitamin D Research

1. Molecular Identity

  • Chemical Name: (3β)-Cholesta-5,7-dien-3-ol
  • CAS Number: 434-16-2
  • Source: Naturally occurring sterol, also synthetically produced for research purposes

2. Biochemical Significance

7-Dehydrocholesterol is a vital intermediate in cholesterol biosynthesis and the immediate precursor to vitamin D3. Its unique molecular structure, featuring two double bonds, makes it a compound of significant interest in nutritional biochemistry, dermatology, and metabolic research.

3. Key Properties of 7-Dehydrocholesterol

  • Vitamin D Precursor: Converts to vitamin D3 upon UV exposure
  • Cholesterol Intermediate: Key molecule in cholesterol biosynthesis pathway
  • UV Sensitivity: Undergoes photochemical reactions with specific wavelengths
  • Membrane Component: Contributes to cellular membrane structure and function

4. Potential Research Applications

  • Vitamin D synthesis and metabolism studies
  • Dermatological research on UV-induced reactions
  • Cholesterol biosynthesis investigations
  • Membrane biology and lipid raft studies

5. Current Research Focus

Ongoing studies are investigating 7-Dehydrocholesterol’s role in:

  • Optimizing vitamin D production in skin
  • Understanding vitamin D deficiency mechanisms
  • Exploring its potential in treating skin disorders
  • Investigating its involvement in neurodevelopmental processes

6. Formulation Challenges and Innovations

Researchers are actively working on:

  • Enhancing stability in various experimental conditions
  • Developing controlled UV exposure methods for vitamin D synthesis
  • Creating targeted delivery systems for dermal applications

7. Regulatory Considerations

7-Dehydrocholesterol (CAS 434-16-2) is primarily used in research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

  • Advanced studies on its role in vitamin D-related disorders
  • Exploration of its potential in personalized vitamin D supplementation
  • Investigation of its interactions with other steroid hormones and membrane components

9. Collaborative Opportunities

We invite nutritional biochemists, dermatologists, endocrinologists, and academic institutions to explore the research potential of 7-Dehydrocholesterol. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with 7-Dehydrocholesterol – a key intermediate at the intersection of vitamin D metabolism, cholesterol biosynthesis, and dermatological studies.