Aloe Emodine: Natural Anthraquinone for Biomedical and Natural Product Research

1. Molecular Identity

• Chemical Name: 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
• CAS Number: 481-72-1
• Source: Found in Aloe vera and species of Rheum (rhubarb), as well as other medicinal plants

2. Biochemical Relevance

Aloe Emodine is a naturally occurring anthraquinone compound known for its distinctive red-orange pigment and structural similarity to other bioactive quinones. It is of interest in phytochemical studies and biological evaluations due to its multifaceted interaction with cellular processes.

3. Functional Properties

• Cytotoxic Activity: Investigated in various cell-based systems
• Inflammatory Modulation: Evaluated for effects on inflammation-related pathways
• Antimicrobial Potential: Studied for its effects on selected bacteria and fungi
• Physiological Activity: Known for mild stimulant-laxative properties

4. Research Application Areas

• Cell biology and oxidative stress models
• Botanical metabolite profiling
• Natural antioxidant and antimicrobial screening
• Studies on gastrointestinal physiology

5. Current Scientific Interest

Ongoing investigations focus on Aloe Emodine’s influence on:

• Mechanistic pathways in cellular metabolism
• Inflammation markers in vitro and ex vivo
• Microbiome interaction studies
• Cellular senescence and age-related research

6. Technical Considerations

• Stability under various pH and solvent conditions
• Solubility optimization for in vitro systems
• Evaluation in compound libraries and botanical extract matrices

7. Regulatory Context

Aloe Emodine (CAS 481-72-1) is primarily used in research settings and in botanical studies. Its inclusion in end-user formulations requires proper toxicological evaluation and must align with local regulatory frameworks, especially within nutraceutical or cosmetic development.

8. Future Research Outlook

Potential research directions include:

• Assessment in model organisms for biological activity
• Investigation of chemical analogues and structure–activity relationships
• Collaborative screening with plant-based compound libraries

9. Collaborative Opportunities

We welcome researchers in phytochemistry, cellular biology, microbiology, and natural product science to explore Aloe Emodine’s broad research potential. For technical data, availability, or collaboration inquiries, please contact us at [email protected].

Explore the intersection of natural product chemistry and cellular biology with Aloe Emodine – a distinctive anthraquinone compound for advanced scientific exploration.