Curcumin: Potent Polyphenol for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• CAS Number: 458-37-7
• Source: Extracted from the rhizomes of Curcuma longa (turmeric)

2. Biochemical Significance

Curcumin is a naturally occurring polyphenol with remarkable biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential therapeutic properties, making it a compound of significant interest in nutritional and pharmaceutical research.

3. Key Properties of Curcumin

• Antioxidant: Exhibits strong free radical scavenging activity
• Anti-inflammatory: Demonstrates ability to modulate multiple inflammatory pathways
• Anticancer Potential: Shows promise in various cancer models
• Neuroprotective: Indicates potential in protecting neuronal cells

4. Potential Research Applications

• Cancer research and chemoprevention studies
• Neurodegenerative disorder investigations
• Cardiovascular health research
• Chronic inflammatory disease studies

5. Current Research Focus

Ongoing studies are investigating Curcumin’s effects on:

• Various cancer types and mechanisms of action
• Alzheimer’s disease and cognitive function
• Metabolic syndrome and diabetes
• Gut health and microbiome modulation

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Curcumin (CAS 458-37-7) is Generally Recognized as Safe (GRAS) by the FDA. Its use in specific therapeutic applications may require additional regulatory approval depending on the jurisdiction and intended use.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific health indications
• Exploration of Curcumin’s potential in personalized medicine
• Investigation of its epigenetic modulation capabilities

9. Collaborative Opportunities

We invite oncologists, neurologists, nutritionists, and academic institutions to explore the research potential of Curcumin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Curcumin – a versatile polyphenol at the forefront of natural product-based therapeutic strategies.