Erianin: Potent Bioactive Compound from Traditional Chinese Medicine

1. Molecular Identity

• Chemical Name: 2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
• CAS Number: 95041-90-0
• Source: Extracted from Dendrobium chrysotoxum, an orchid used in Traditional Chinese Medicine

2. Biochemical Significance

Erianin is a bibenzyl compound derived from orchids, known for its diverse pharmacological activities. Its unique molecular structure contributes to its potent anticancer, anti-inflammatory, and antioxidant properties, making it a compound of significant interest in natural product research and potential therapeutic development.

3. Key Properties

• Anticancer Potential: Demonstrates cytotoxicity against various cancer cell lines
• Anti-angiogenic: Inhibits formation of new blood vessels in tumors
• Anti-inflammatory: Modulates inflammatory responses
• Antioxidant: Exhibits free radical scavenging activity

4. Potential Research Applications

• Cancer research and drug development
• Angiogenesis inhibition studies
• Inflammatory disorder investigations
• Neurodegenerative disease research

5. Current Research Focus

Ongoing studies are investigating Erianin’s effects on:

• Various cancer types and mechanisms of action
• Tumor microenvironment and metastasis
• Neuroprotection in cognitive disorders
• Cellular stress responses and apoptosis pathways

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability and stability
• Developing targeted delivery systems for improved efficacy
• Creating synergistic combinations with other anticancer agents

7. Regulatory Considerations

As a compound derived from Traditional Chinese Medicine, Erianin (CAS 95041-90-0) is primarily used in research settings. Its development for therapeutic applications would require extensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced preclinical and potential clinical trials for specific cancer indications
• Exploration of Erianin’s potential in combination therapies
• Development of semi-synthetic derivatives with enhanced properties

9. Collaborative Opportunities

We invite researchers, pharmaceutical companies, and academic institutions to explore the research potential of Erianin. For inquiries, collaborations, or to discuss how Erianin can benefit your research projects, please contact us at [email protected].

Join us in unlocking the full potential of Erianin – a promising natural compound at the forefront of cancer research and innovative therapeutic strategies.