Phosphatidylethanolamine (PE): Core Phospholipid for Advanced Membrane Studies

1. Molecular Identity

• Chemical Name: 1,2-diacyl-sn-glycero-3-phosphoethanolamine
• CAS Number: 39382-08-6 (common form)
• Source: Naturally found in cell membranes; also available via synthetic production

2. Scientific Relevance

Phosphatidylethanolamine (PE) is a key structural phospholipid and ranks among the most abundant components of eukaryotic membranes. Its physicochemical properties influence membrane curvature, dynamics, and protein interactions, making it indispensable in fundamental and applied lipid research.

3. Key Research Properties

• Membrane Curvature: Contributes to bilayer architecture and dynamics
• Cellular Function: Plays a role in vesicle formation and membrane fusion
• Protein Interaction: Modulates activity and localization of membrane-associated proteins
• Autophagy Research: Implicated in autophagosome membrane structure

4. Potential Research Applications

• Biomembrane modeling and synthetic biology
• Studies on vesicle trafficking and membrane-associated events
• Neuroscience-focused investigations on membrane composition
• Liposome engineering and nanocarrier development

5. Current Research Topics

PE is being studied in contexts such as:

• Mitochondrial membrane integrity and lipid exchange
• Membrane remodeling during stress adaptation
• Role in intracellular signaling pathways
• Formation and function of model lipid systems

6. Formulation and Experimental Innovations

Recent advances focus on:

• Stabilized PE dispersions for in vitro use
• PE-enriched liposomes for targeted material delivery
• Optimized protocols for PE incorporation in lipid bilayers

7. Usage and Compliance Notes

Phosphatidylethanolamine (CAS 39382-08-6) is provided for laboratory and R&D use. Any application involving regulated pathways requires validation and approval according to relevant standards and jurisdiction.

8. Emerging Research Directions

The research community is exploring:

• PE dynamics in complex lipid environments
• Customized PE derivatives for experimental modulation
• Potential use of PE as a component in diagnostic platforms

9. Collaborative Opportunities

We welcome researchers in lipidomics, cellular biology, membrane biophysics, and pharmaceutical technology to explore Phosphatidylethanolamine’s potential. For technical inquiries, product specifications, or collaboration opportunities, contact us at [email protected].

Advance your membrane and lipid research with high-purity Phosphatidylethanolamine – engineered for performance in complex experimental systems.