Cholesterol: Fundamental Sterol for Advanced Biochemical Research
1. Molecular Identity
- Chemical Name: (3β)-Cholest-5-en-3-ol
- CAS Number: 57-88-5
- Source: Biosynthesized in animal cells; also available from various animal-derived foods
2. Biochemical Significance
Cholesterol is a crucial sterol molecule with diverse biological functions. Its unique structure serves as a precursor for steroid hormones, bile acids, and vitamin D, making it an essential compound in cellular biology and physiological research.
3. Key Properties of Cholesterol
- Membrane Fluidity: Regulates cell membrane properties
- Precursor Molecule: Essential for steroid hormone and bile acid synthesis
- Lipid Raft Formation: Involved in cellular signaling and protein trafficking
- Emulsification: Aids in the absorption of dietary fats
4. Potential Research Applications
- Cardiovascular disease studies
- Membrane biology investigations
- Endocrinology and hormone research
- Lipid metabolism and transport studies
5. Current Research Focus
Ongoing studies are investigating cholesterol’s role in:
- Atherosclerosis and heart disease mechanisms
- Neurodegenerative disorders
- Cancer cell metabolism
- Intracellular cholesterol trafficking
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Developing cholesterol-based nanocarriers for drug delivery
- Creating synthetic cholesterol analogs for various applications
- Optimizing cholesterol quantification methods
7. Regulatory Considerations
Cholesterol (CAS 57-88-5) is widely recognized as a research chemical. Its use in specific pharmaceutical or food applications may require additional regulatory approval depending on the jurisdiction and intended use.
8. Future Research Directions
The scientific community anticipates:
- Advanced studies on cholesterol’s role in brain function and neurological disorders
- Exploration of targeted cholesterol modulation in disease treatment
- Investigation of cholesterol’s involvement in immune system regulation
9. Collaborative Opportunities
We invite biochemists, cell biologists, pharmacologists, and academic institutions to explore the research potential of cholesterol. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biochemical research with cholesterol – a fundamental sterol at the core of cellular biology and physiology.