Squalene: Essential Triterpene for Bulk Research and Cosmetic Applications

1. Molecular Identity

• Chemical Name: 2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene
• CAS Number: 111-02-4
• Source: Found in shark liver oil, olive oil, and plant sources; also produced by human sebaceous glands

2. Scientific Significance

Squalene is a natural triterpene hydrocarbon that serves as a biosynthetic intermediate in sterol and lipid metabolism. Its structural versatility and skin-friendly properties make it widely studied in research on oxidative stress, delivery systems, and dermatological science.

3. Key Properties

• Antioxidant: Neutralizes free radicals and reduces oxidative stress
• Skin Compatibility: Enhances skin hydration and softness
• Emollient: Widely used in moisturizers and skincare formulations
• Adjuvant Role: Investigated in vaccine delivery systems

4. Research and Industrial Applications

• Cosmetic and personal care formulation studies
• Adjuvant component in vaccine delivery systems
• Lipid metabolism and cholesterol pathway research
• Oxidative stability testing and skin protection studies

5. Ongoing Research Focus

Current scientific interest includes:

• Photoprotection and anti-aging mechanisms
• Biological membrane dynamics and squalene’s role
• Stability in emulsions and oxidative environments
• Eco-friendly extraction and biosynthesis

6. Bulk Supply and Technical Characteristics

• Availability: Offered in bulk quantities (grams to kilograms) for industrial and academic research
• Stability: Requires antioxidant protection in storage and formulation
• Quality: Supplied with high purity, suitable for formulation testing and analytical R&D

7. Regulatory Status

Squalene (CAS 111-02-4) is Generally Recognized as Safe (GRAS) for food and cosmetic use. Its role in research or industrial development is governed by regional regulations. Not for human consumption or clinical use without proper approval.

8. Future Perspectives

Anticipated directions include:

• Development of squalene-based nanocarriers and emulsions
• Studies on age-related processes and membrane fluidity
• Formulation optimization for sustainable and vegan sources

9. Contact and Bulk Orders

NST Chemicals supplies Squalene in bulk for research, formulation, and technical applications. For quotes, documentation, or collaboration, please contact us at [email protected].

Unlock the potential of Squalene — a multifunctional triterpene supporting innovation in cosmetic science, formulation research, and industrial product development.