|Appearance||White to off-white powder|
|Storage||+2 … +8 °C|
Download the Quality Specification there: QS 473-98-3.pdf
Betulin (Betulinol) CAS: 473-98-3 is a natural, abundant pentacyclic triterpenoid. It can be found in various sources in nature too, but most commonly can be found in a family of Betulaceae. Indeed, it is a compound, that gives birch bark its characteristic white color.
Betulin, firstly was discovered back in 1788 by German scientist Johann Tobias Lowitz, but its positive biological effects have been known much longer. Therefore, extracts of birch bark have been long used in traditional medicine for various skin diseases. Above all, as betulin comprises up to 28% of dry birch bark, most of the positive effects are caused by it.
Moreover, in vitro studies shows, that betulin is effective against various type of cancer cells. Its main action is induction of programmed cell death – apoptosis and slowing down the progress of tumor formation (DOI: 10.1016/j.ejps.2006.04.006). Furthermore, several other properties can be assigned to it – anti-inflammatory, anti-viral, etc.
Betulinol can be used for the synthesis of semi-synthetic compounds for further biological activity enhancements.