Flaxseed Lignans (SDG): Nature’s Powerful Phytoestrogens for Health Research

1. Molecular Identity

• Chemical Name: Secoisolariciresinol diglucoside (SDG)
• CAS Number: 158932-33-3
• Source: Extracted from flaxseed (Linum usitatissimum)

2. Biochemical Significance

Flaxseed lignans, primarily secoisolariciresinol diglucoside (SDG), are phytoestrogens with unique molecular structures. Their ability to be metabolized into mammalian lignans and their potent antioxidant properties make them compounds of significant interest in nutrition, health, and disease prevention research.

3. Key Properties

• Phytoestrogen: Exhibits weak estrogenic and anti-estrogenic effects
• Antioxidant: Demonstrates potent free radical scavenging activity
• Anti-inflammatory: Shows potential in reducing inflammation
• Metabolic Precursor: Converts to enterodiol and enterolactone in the gut

4. Potential Research Applications

• Cardiovascular health studies
• Cancer prevention research
• Menopausal symptoms management
• Metabolic syndrome and diabetes investigations

5. Current Research Focus

Ongoing studies are investigating Flaxseed Lignans’ effects on:

• Breast and prostate cancer risk reduction
• Cholesterol levels and arterial health
• Bone density and osteoporosis prevention
• Insulin sensitivity and glucose metabolism

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability and absorption
• Developing standardized extracts for research purposes
• Creating stable formulations for various applications

7. Regulatory Considerations

Flaxseed and its components are Generally Recognized as Safe (GRAS) by the FDA. Specific health claims may require additional regulatory approval depending on the jurisdiction and intended use.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific health indications
• Exploration of synergistic effects with other bioactive compounds
• Investigation of gut microbiome interactions and prebiotic potential

9. Collaborative Opportunities

We invite nutritionists, health researchers, pharmaceutical companies, and academic institutions to explore the research potential of Flaxseed Lignans (SDG). For inquiries, collaborations, or to discuss how Flaxseed Lignans (CAS 58932-33-3) can benefit your research or product development, please contact us at [email protected].

Join us in unlocking the full potential of Flaxseed Lignans – natural compounds at the forefront of nutrition and preventive health research.