Glycyrrhetinic Acid (CAS 471-53-4): Functional Triterpenoid for Biomedical and Botanical Research

1. Molecular Identity

• Chemical Name: 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid
• CAS Number: 471-53-4
• Source: Naturally derived from licorice root (Glycyrrhiza glabra)

2. Scientific Relevance

Glycyrrhetinic acid is a pentacyclic triterpenoid with a well-established presence in natural product libraries. Its molecular framework has attracted interest in formulation development, biochemical pathway research, and botanical activity profiling.

3. Investigated Research Properties

• Inflammatory Pathway Studies: Included in in vitro screening assays
• Liver System Models: Studied for interactions with hepatic enzymes
• Topical Formulations: Used in skin-related application systems
• Antiviral and Cellular Research: Examined in plant compound interaction panels

4. Application Areas

• Natural compound screening in inflammation-focused studies
• Botanical component evaluation in hepatic and metabolic models
• Formulation development in dermal and cosmetic research
• Experimental design in cellular modulation and growth analysis

5. Active Research Topics

• Signal pathway modulation and biochemical mapping
• Cell-based liver research using phytocompound frameworks
• Barrier-supportive skin formulation modeling
• Investigative pathways for compound behavior in vitro

6. Formulation Insights

• Delivery Systems: Explored for targeted and enhanced uptake
• Stability Engineering: Applied to various product formats
• Synergy Development: Studied in conjunction with complementary bioactives

7. Regulatory Considerations

Glycyrrhetinic Acid (CAS 471-53-4) is available for use in cosmetic, industrial, and research settings. Regulatory classification may vary depending on jurisdiction and application context. Documentation is available to support safety and compliance reviews.

8. Future Research Focus

• Expanded evaluation in liver system and inflammation models
• Research into multi-pathway botanical interactions
• Mechanistic studies at the cellular and molecular levels

9. Partnership Opportunities

NST Chemicals offers high-purity Glycyrrhetinic Acid for research institutions and formulation developers. For bulk orders, technical data, or collaborative discussions, contact us at [email protected].

Explore the potential of Glycyrrhetinic Acid – a triterpenoid with functional relevance in botanical and biomedical research.