Huperzine A: Alkaloid for Advanced Neurobiology and Memory Research

1. Molecular Identity

• Chemical Name: (1R,9S,13E)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0²,⁷]trideca-2(7),3,10-trien-5-one
• CAS Number: 102518-79-6
• Source: Isolated from Huperzia serrata (Chinese club moss)

2. Biochemical and Research Significance

Huperzine A is a sesquiterpene alkaloid known for its strong interaction with acetylcholinesterase (AChE). Its selectivity and reversible binding profile make it valuable in neurochemical studies and learning-related biochemical models.

3. Key Characteristics

• AChE Inhibitor: High-affinity binding to acetylcholinesterase
• Neuronal Relevance: Investigated in neuron survival and oxidative stress studies
• Memory Research: Studied for its role in modulating cholinergic pathways
• Receptor Interactions: Explored for NMDA receptor activity modulation

4. Application Areas

• Neurochemical and memory pathway research
• Studies on learning mechanisms and synaptic plasticity
• Biochemical models of neuroprotection
• Evaluation of acetylcholine signaling modulation

5. Current Research Focus

Ongoing investigations involve:

• Cholinergic system regulation and synaptic activity
• In vitro models of oxidative stress and neuronal viability
• Studies in chemically induced neurotoxicity
• Formulation and delivery optimization for laboratory use

6. Bulk Availability and Specifications

• Form: Solid (≥98% purity, HPLC)
• Use: For laboratory research only
• Packaging: Available in mg to bulk-scale quantities
• Documentation: COA, MSDS, and technical data on request

7. Safety and Regulatory Status

Huperzine A (CAS 102518-79-6) is offered exclusively for research and analytical applications. It is not intended for human consumption or use in food, feed, or personal care formulations.

8. Research Outlook

Potential future directions include:

• Cholinergic pathway mapping in neurochemical models
• Combination studies with other bioactive natural compounds
• Expanded use in neurobiology and synaptic signaling assays

9. Collaborative Opportunities

We welcome collaboration with neuroscience researchers, academic labs, and biochemical development teams. For product requests, documentation, or bulk supply inquiries, contact us at [email protected].

Advance your neurochemical research with Huperzine A – a precision alkaloid for cognitive and synaptic studies.