Macranthoidin B: Complex Triterpenoid Saponin for Advanced Phytochemical Research

1. Molecular Identity

• Chemical Name: 3-O-{β-D-Glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-α-L-arabinopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester
• CAS Number: 136849-88-2
• Source: Isolated from Lonicera macranthoides (honeysuckle species)

2. Biochemical Significance

Macranthoidin B is a naturally occurring triterpenoid saponin known for its complex glycosylated structure and presence in traditional medicinal plants. It has become a subject of growing interest in phytochemistry, analytical research, and botanical quality control.

3. Key Research Properties

• Oleanolic Acid Core: Structured around a bioactive triterpenoid scaffold
• Multiple Glycosides: Contains diverse sugar moieties contributing to solubility and activity
• Botanical Marker: Used as a phytochemical reference compound in honeysuckle extract analysis
• Natural Compound: Valuable for profiling plant secondary metabolites

4. Research Applications

• Phytochemical and structural elucidation studies
• Saponin structure–activity relationship (SAR) research
• Traditional Chinese Medicine (TCM) compound analysis
• Screening studies for natural product bioactivity

5. Current Areas of Investigation

Researchers are exploring Macranthoidin B in relation to:

• Anti-inflammatory and immunomodulatory models
• Synergistic studies with other botanical compounds
• Antiviral screening, including influenza-related assays
• Secondary metabolite function in plant defense

6. Bulk Supply and Product Format

• Form: Off-white to light yellow powder
• Purity: ≥98% (HPLC)
• Availability: Bulk quantities available on request
• Intended Use: For laboratory research and industrial R&D use only

7. Technical and Regulatory Notes

Macranthoidin B (CAS 136849-88-2) is intended exclusively for scientific research. It is not approved for human or veterinary use. All users are responsible for regulatory compliance in their respective regions.

8. Future Research Potential

The scientific community is investigating:

• Analytical standard development and reference profiling
• Semi-synthetic modifications for improved solubility and analytical performance
• Comparative studies among saponins from various Lonicera species

9. Collaboration Opportunities

We invite phytochemists, natural product researchers, TCM analysts, and academic partners to explore the full research potential of Macranthoidin B. For technical details, quotations, or bulk supply inquiries, please contact us at [email protected].

Partner with us to explore Macranthoidin B – a high-purity triterpenoid saponin supporting the advancement of botanical and natural compound research.