Protocatechuic aldehyde: Potent Phenolic Compound for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 3,4-Dihydroxybenzaldehyde
• CAS Number: 139-85-5
• Source: Naturally occurring in various plants, including Salvia miltiorrhiza (red sage)

2. Biochemical Significance

Protocatechuic aldehyde is a phenolic aldehyde with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential cardioprotective properties, making it a compound of significant interest in pharmaceutical research and natural product studies.

3. Key Properties of Protocatechuic aldehyde

• Antioxidant: Exhibits strong free radical scavenging ability
• Anti-inflammatory: Demonstrates potential to modulate inflammatory pathways
• Cardioprotective: Shows promise in protecting cardiovascular tissues
• Neuroprotective: Indicates efficacy in protecting neuronal cells

4. Potential Research Applications

• Cardiovascular disease studies
• Neurodegenerative disorder investigations
• Cancer research
• Anti-aging and oxidative stress studies

5. Current Research Focus

Ongoing studies are investigating Protocatechuic aldehyde’s effects on:

• Oxidative stress and antioxidant defense mechanisms
• Inflammatory signaling pathways in various tissues
• Cardioprotection against ischemia-reperfusion injury
• Neuroprotection in models of neurodegenerative diseases

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other antioxidant compounds

7. Regulatory Considerations

Protocatechuic aldehyde (CAS 139-85-5) is primarily used in research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for cardiovascular and neurodegenerative disorders
• Exploration of Protocatechuic aldehyde’s potential in combination therapies
• Investigation of its mechanisms of action at the molecular level

9. Collaborative Opportunities

We invite cardiologists, neurologists, oncologists, and academic institutions to explore the research potential of Protocatechuic aldehyde. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Protocatechuic aldehyde – a powerful phenolic compound at the forefront of natural product-based therapeutic strategies.