Tabersonine CAS 4429-63-4

1785

Synonyms: Tabersonin

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500 g € 1785
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Cat. No. NST-10-131
CAS 4429-63-4
Purity 98% (HPLC)
Appearance Off white powder
Molecular formula C21H24N2O2
Molecular weight 336,43
Storage +2 … +8 °C

Certificate of analysis available by request to [email protected]

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Description

Tabersonine: Potent Alkaloid for Advanced Pharmaceutical Research

1. Molecular Identity

  • Chemical Name: (2R,3R,7aS,14bR,15S)-3-ethenyl-1,2,3,4,5,6,7,7a-octahydro-15-methyl-12H-indolo[2,3-a]quinolizine
  • CAS Number: 4429-63-4
  • Source: Extracted from Voacanga africana and various Tabernaemontana species

2. Biochemical Significance

Tabersonine is an indole alkaloid with a unique molecular structure. Its presence as a precursor in the biosynthesis of important pharmaceutical compounds makes it a significant target in natural product research and drug development studies.

3. Key Properties of Tabersonine

  • Biosynthetic Precursor: Key intermediate in the synthesis of vindoline and vinblastine
  • Potential Anticancer Activity: Shows promise in various cancer models
  • Antimicrobial Properties: Demonstrates activity against certain pathogens
  • Neurological Effects: Indicates potential impacts on the central nervous system

4. Potential Research Applications

  • Cancer research and drug development
  • Antimicrobial compound screening
  • Neuropharmacological studies
  • Plant alkaloid biosynthesis investigations

5. Current Research Focus

Ongoing studies are investigating tabersonine’s role in:

  • Synthesis of novel anti-cancer agents
  • Elucidation of alkaloid biosynthetic pathways
  • Development of new antimicrobial compounds
  • Exploration of neurological effects and potential applications

6. Formulation Challenges and Innovations

Researchers are actively working on:

  • Improving extraction and purification methods
  • Developing semi-synthetic derivatives with enhanced properties
  • Creating stable formulations for various research applications

7. Regulatory Considerations

As a natural alkaloid, tabersonine’s (CAS 4429-63-4) regulatory status is primarily focused on research use. Any therapeutic applications would require extensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

  • Advanced studies on the anticancer potential of tabersonine and its derivatives
  • Exploration of its role in developing new antimicrobial agents
  • Investigation of potential applications in neuropharmacology

9. Collaborative Opportunities

We invite pharmaceutical researchers, natural product chemists, and academic institutions to explore the research potential of tabersonine. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing pharmaceutical research with tabersonine – a key alkaloid at the forefront of natural product-based drug discovery.