2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside: Potent Stilbene Glycoside for Advanced Biomedical Research
1. Molecular Identity
- Chemical Name: 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG)
- CAS Number: 82373-94-2
- Source: Extracted from Polygonum multiflorum (He Shou Wu) and other Polygonum species
2. Biochemical Significance
TSG is a stilbene glycoside with a unique molecular structure that contributes to its diverse biological activities. Its presence in traditional Chinese medicine, particularly in Polygonum multiflorum, makes it a compound of significant interest in natural product research and potential therapeutic applications.
3. Key Properties
- Antioxidant: Exhibits potent free radical scavenging activity
- Neuroprotective: Shows promise in protecting neuronal cells
- Cardioprotective: Demonstrates potential in supporting cardiovascular health
- Anti-aging: Indicates effects on various aging-related processes
4. Potential Research Applications
- Neurodegenerative disease studies
- Cardiovascular health research
- Anti-aging and longevity investigations
- Liver function and metabolism studies
5. Current Research Focus
Ongoing studies are investigating TSG’s effects on:
- Alzheimer’s and Parkinson’s disease models
- Atherosclerosis and cardiac function
- Cellular senescence and telomere maintenance
- Hepatoprotection and lipid metabolism
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing bioavailability and stability
- Developing targeted delivery systems for improved efficacy
- Creating synergistic combinations with other bioactive compounds
7. Regulatory Considerations
As a naturally occurring compound, TSG’s regulatory status is evolving. Its use in specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced preclinical and potential clinical trials for neurodegenerative and cardiovascular indications
- Exploration of TSG’s potential in anti-aging therapies
- Investigation of structure-activity relationships for optimized derivatives
9. Collaborative Opportunities
We invite neuroscientists, cardiologists, gerontologists, and academic institutions to explore the research potential of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside. For inquiries, collaborations, or to discuss how TSG can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biomedical research with 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside – a promising stilbene glycoside at the intersection of traditional medicine and modern therapeutic strategies.