2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside: Potent Stilbene Glycoside for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside
• CAS Number: 82373-94-2
• Molecular Formula: C20H22O9
• Source: Naturally occurring in Polygonum multiflorum (He Shou Wu) and other Polygonum species

2. Biochemical Significance

2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside is a stilbene glycoside with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-aging, and potential neuroprotective properties, making it a compound of significant interest in pharmaceutical research and traditional medicine studies.

3. Key Properties of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside

• Antioxidant: Exhibits strong free radical scavenging ability
• Anti-aging: Demonstrates potential to slow cellular senescence
• Neuroprotective: Shows promise in protecting neuronal cells
• Cardioprotective: Indicates efficacy in improving cardiovascular health

4. Potential Research Applications

• Neurodegenerative disorder studies
• Anti-aging and longevity research
• Cardiovascular disease investigations
• Liver function and protection studies

5. Current Research Focus

Ongoing studies are investigating 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside’s effects on:

• Neuroprotection mechanisms in various brain disorders
• Cellular senescence and telomere maintenance
• Lipid metabolism and atherosclerosis progression
• Hepatic enzyme activities and liver function

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (82373-94-2) is primarily used in research settings and traditional medicine. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for neurodegenerative and age-related disorders
• Exploration of its potential in combination therapies
• Investigation of its long-term effects on health and longevity

9. Collaborative Opportunities

We invite neurologists, gerontologists, cardiologists, and academic institutions to explore the research potential of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside – a powerful stilbene glycoside at the forefront of natural product-based therapeutic strategies.