Tizanidine Hydrochloride : Potent Centrally Acting Muscle Relaxant for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
• CAS Number: 64461-82-1
• Source: Synthetic compound

2. Biochemical Significance

Tizanidine Hydrochloride is a centrally acting α2 adrenergic agonist with potent muscle relaxant properties. Its unique molecular structure contributes to its ability to reduce spasticity and muscle tone, making it a compound of significant interest in neurological and musculoskeletal research.

3. Key Properties of Tizanidine Hydrochloride

• Muscle Relaxant: Exhibits strong ability to reduce muscle spasticity
• α2 Adrenergic Agonist: Demonstrates selective action on α2 receptors
• Analgesic Effects: Shows potential in pain management
• Short Half-life: Indicates rapid onset and offset of action

4. Potential Research Applications

• Spasticity disorder studies
• Chronic pain investigations
• Neurological research
• Musculoskeletal disorder studies

5. Current Research Focus

Ongoing studies are investigating Tizanidine Hydrochloride’s effects on:

• Mechanisms of action in various spasticity conditions
• Potential applications in neuropathic pain
• Comparative efficacy with other muscle relaxants
• Drug interactions and safety profiles

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Developing extended-release formulations
• Exploring alternative routes of administration
• Creating combination therapies for enhanced efficacy

7. Regulatory Considerations

Tizanidine Hydrochloride (CAS 64461-82-1) is an approved drug in many countries. Its development for new therapeutic applications or formulations would require additional safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for new indications
• Exploration of Tizanidine’s potential in combination therapies
• Investigation of its long-term effects and safety profile

9. Collaborative Opportunities

We invite neurologists, pain specialists, pharmacologists, and academic institutions to explore the research potential of Tizanidine Hydrochloride. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Tizanidine Hydrochloride – a powerful muscle relaxant at the forefront of neurological and musculoskeletal research strategies.