Icariin: Potent Flavonoid for Cutting-Edge Biomedical Research
1. Molecular Identity
- Chemical Name: 8-Prenylkaempferol-3,7-O-diglucoside
- CAS Number: 489-32-7
- Source: Isolated from Epimedium species, commonly known as Horny Goat Weed
2. Biochemical Significance
Icariin is a prenylated flavonoid glycoside with diverse biological activities. Its unique molecular structure contributes to its potential aphrodisiac, neuroprotective, and bone-strengthening properties, making it a compound of significant interest in pharmaceutical research and traditional medicine studies.
3. Key Properties of Icariin
- PDE5 Inhibition: Demonstrates potential in improving erectile function
- Neuroprotective: Shows promise in protecting neuronal cells
- Osteogenic: Exhibits ability to promote bone formation
- Antioxidant: Indicates free radical scavenging capabilities
4. Potential Research Applications
- Erectile dysfunction studies
- Neurodegenerative disease investigations
- Osteoporosis and bone health research
- Cardiovascular health studies
5. Current Research Focus
Ongoing studies are investigating Icariin’s effects on:
- Nitric oxide signaling pathways in vascular function
- Neuroprotection mechanisms in various brain disorders
- Bone metabolism and osteoblast activity
- Antioxidant and anti-inflammatory processes
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing bioavailability through novel delivery systems
- Developing stable formulations for various applications
- Creating semi-synthetic derivatives with improved pharmacological profiles
7. Regulatory Considerations
Icariin (CAS 489-32-7) is primarily used in research settings and traditional medicine. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced clinical trials for erectile dysfunction and osteoporosis
- Exploration of Icariin’s potential in combination therapies
- Investigation of its mechanisms of action at the molecular level
9. Collaborative Opportunities
We invite urologists, neurologists, orthopedic researchers, and academic institutions to explore the research potential of Icariin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biomedical research with Icariin – a powerful flavonoid at the forefront of natural product-based therapeutic strategies.