Baicalein: Potent Flavonoid for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 5,6,7-Trihydroxyflavone
• CAS Number: 491-67-8
• Source: Naturally occurring in the roots of Scutellaria baicalensis and other Scutellaria species

2. Biochemical Significance

Baicalein is a flavonoid with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential anticancer properties, making it a compound of significant interest in pharmaceutical research and natural product studies.

3. Key Properties of Baicalein

• Antioxidant: Exhibits strong free radical scavenging ability
• Anti-inflammatory: Demonstrates potential to modulate inflammatory pathways
• Neuroprotective: Shows promise in protecting neuronal cells
• Anticancer: Indicates efficacy against various cancer cell lines

4. Potential Research Applications

• Neurodegenerative disorder studies
• Cancer research and drug development
• Cardiovascular disease investigations
• Inflammatory condition research

5. Current Research Focus

Ongoing studies are investigating Baicalein’s effects on:

• Cellular antioxidant defense mechanisms
• Inflammatory signaling pathways in various tissues
• Apoptosis induction in cancer cells
• Neuroprotection in models of neurodegenerative diseases

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Baicalein (CAS 491-67-8) is primarily used in research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for neurodegenerative and inflammatory disorders
• Exploration of Baicalein’s potential in combination cancer therapies
• Investigation of its mechanisms of action at the molecular level

9. Collaborative Opportunities

We invite neurologists, oncologists, pharmacologists, and academic institutions to explore the research potential of Baicalein. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Baicalein – a powerful flavonoid at the forefront of natural product-based therapeutic strategies.