NST Chemicals
  • Home
  • Products
  • Botanical Extracts
  • Blog
  • Contact Us
0 items / €0
Daidzein CAS 486-66-8
Home Flavonoids Daidzein
Andrographolide CAS 5508-58-7
Andrographolide €120 – €540
Back to products
Chenodeoxycholic Acid CAS 474-25-9
Chenodeoxycholic Acid €120 – €590

Daidzein

€110 – €510

Clear

Synonyms: 4′,7-Dihydroxyisoflavone

50 g € 110
100 g € 150
250 g € 280
500 g € 510
For kilogram quantities contact us at sales@nstchemicals.com
Cat. No. NST-10-15
CAS 486-66-8
Purity 98% (HPLC)
Appearance White to off-white powder
Molecular formula C15H10O4
Molecular weight 254,24
Storage +2 … +8 °C

Certificate of analysis available by request to sales@nstchemicals.com

SKU: N/A Categories: All products, Flavonoids
  • Description
Description

What is Daidzein?

Daidzein is a natural substance from the isoflavone compound class. Typically in nature, it can be found in soy un mung beans. Due to daidzein structure similarities with estrogen, its main biological activity is being phytoestrogen. From Chinese traditional medicine, daidzein has been used for the treatment of:

  • fever
  • acute dysentery
  • diarrhea
  • diabetes
  • cardiac disfunction
  • liver failure
  • and more.

However, nowadays medicinal chemists are exploring much broader and more complex use of daidzein.

Anticancer activity of Daidzein

Daidzein supplements have attracted high attention for their anti-cancer properties. Studies have shown that breast cancer is much less common in women from Asia compared to the rest of the world due to the high consumption of phytoestrogens.

Indeed, looking deeper in daidzein activity, scientists were able to identify at least two cellular pathways how it’s inhibiting the spread of breast cancer tissue. Moreover, metabolites of daidzein were found to be even more active and were able to inhibit MMP-2 and MMP-9 that are involved in the spread of cancer tissue.

On the other hand, daidzein was found to be able to induce other cellular pathways responsible for the apoptosis of cancer cells by changing the oxidative potential of cancer cells leading to the death of those cells.

Daidzein was found to also be effective against neuroblastoma, prostate, colon, and other types of cancer.

Daidzein to prevent cardiovascular diseases

Coronary heart disease, atherosclerosis, and other cardiovascular diseases could be classified as estrogen-related. And as hormone replacement therapy has not given a clear path in clinical trials, daidzein could show promise in such treatment for post-menopause women.

Scientists have identified, that daidzein is effective to reduce triglyceride levels for patients with high cholesterol, improving endothelium dysfunction by increasing NO bioabsorption, therefore, leading to vasodilatation. 

Apart from that, daidzein also exhibited excellent effects as a pretreatment for ischemia in rat models. Daidzein improved myocardial contractile dysfunction inhibited myocardial apoptosis and decreases myocardial infarct size.

Osteoporosis treatment with daidzein

A decrease in the density of bones especially for women during and post-menopause is a risk. However, as we mentioned, this deficiency could be treated with daidzein. 

Studies with daidzein showed, that it was able to inhibit bone resorption, promote bone mineralization and increase secretion of osteoprotegerins and RANK ligand, which are responsible for osteoblast differentiation and function. 

Scientists showed that similar effects have been observed in male rats as well, showing that daidzein could be a feasible treatment for male osteoporosis. 

Anti-diabetic effect of daidzein

Scientists are sure, that soy phytoestrogens play a significant role for patients with type-2 diabetes. Tests have shown, that indeed daidzein shows an anti-hyperglycemic effect by increasing blood sugar levels. 

Another group of scientists found that the anti-diabetic effect is also associated with my modulating liver glucose and lipid levels and metabolisms by the direct effect on corresponding enzymes.

Daidzein has also shown potential for patients with type-1 diabetes by promoting the health of pancreatic β-cells and insulin secretion while having no effect on glucagon in non-obese diabetic mice.

The anti-oxidative activity of daidzein

Like other flavones and isoflavones, daidzein due to its structure is considered to possess anti-oxidative properties. 

Scientists found that not only by directly absorbing reactive radical molecules, daidzein was also able to improve our body’s natural ability to fight oxidative stress and such.

In conclusion

Here we have discussed a wide variety of biological activities that daidzein possesses but that’s not only it. Scientists have also identified its anti-inflammatory, neuroprotective, and more and the research is still going strong. If you want to explore the possibilities of daidzein, visit our store for the high-quality products for you to buy.

Related products

Icariin CAS 489-32-7
Quick view

Icariin

€70 – €350
Select options
Dihydromyricetin CAS 27200-12-0
Quick view

Dihydromyricetin

€80 – €400
Select options
Baicalein CAS 491-67-8
Quick view

Baicalein

€90 – €440
Select options
Taxifolin CAS 480-18-2
Quick view

Taxifolin

€70 – €330
Select options
Eupatilin CAS 22368-21-4
Quick view

Eupatilin

€60 – €270
Select options
Luteolin CAS 491-70-3
Quick view

Luteolin

€90 – €440
Select options
Genistein CAS 446-72-0
Quick view

Genistein

€110 – €520
Select options
Icaritin CAS 118525-40-9
Quick view

Icaritin

€280 – €1340
Select options


Have Questions? We are Here to Help You!

Nature Science Technologies is among the world’s leading companies for Betulin derivatives
CONTACT US

INFORMATIONAL LINKS

    • Home
    • About Us
    • Blog
    • Products
    • Projects
    • Privacy Policy
    • Contact Us

CONTACT INFORMATION

Address
Rupnicu 4, Olaine, LV-2114, Latvia
539 W. Commerce St #7697, Dallas, TX 75208
Email Address
sales@nstchemicals.com

Phone Number
+371 24220280
+1 (469) 972-7062

Nature Science Technologies 2023. All Rights Reserved.
Shopping cart
close