Tangeretin: Potent Polymethoxyflavone for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 5,6,7,8,4′-Pentamethoxyflavone
• CAS Number: 481-53-8
• Source: Naturally occurring in citrus fruits, especially tangerine and other orange peels

2. Biochemical Significance

Tangeretin is a polymethoxylated flavone with diverse biological activities. Its unique molecular structure contributes to its potential anti-inflammatory, neuroprotective, and anticancer properties, making it a compound of significant interest in pharmaceutical research and nutraceutical studies.

3. Key Properties of Tangeretin

• Anti-inflammatory: Demonstrates ability to modulate inflammatory pathways
• Neuroprotective: Shows promise in protecting neuronal cells
• Anticancer: Exhibits potential in inhibiting various cancer cell lines
• Antioxidant: Indicates free radical scavenging capabilities

4. Potential Research Applications

• Neurodegenerative disease studies
• Cancer research and drug development
• Cardiovascular health investigations
• Metabolic disorder research

5. Current Research Focus

Ongoing studies are investigating Tangeretin’s effects on:

• Neuroinflammatory processes in brain disorders
• Cancer cell proliferation and metastasis
• Lipid metabolism and atherosclerosis
• Glucose homeostasis and insulin sensitivity

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other flavonoids

7. Regulatory Considerations

Tangeretin (CAS 481-53-8) is primarily used in research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for neurodegenerative and metabolic disorders
• Exploration of Tangeretin’s potential in combination cancer therapies
• Investigation of its mechanisms of action at the molecular level

9. Collaborative Opportunities

We invite neurologists, oncologists, cardiologists, and academic institutions to explore the research potential of Tangeretin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Tangeretin – a powerful polymethoxyflavone at the forefront of natural product-based therapeutic strategies.