Formononetin: Potent Isoflavone for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 7-Hydroxy-3-(4-methoxyphenyl)chromone
• CAS Number: 485-72-3
• Molecular Formula: C16H12O4
• Source: Naturally occurring in various legumes, including red clover and soy

2. Biochemical Significance

Formononetin is an isoflavone with diverse biological activities. Its unique molecular structure contributes to its potential phytoestrogenic, antioxidant, and anticancer properties, making it a compound of significant interest in pharmaceutical research and nutraceutical studies.

3. Key Properties of Formononetin

• Phytoestrogenic: Demonstrates ability to interact with estrogen receptors
• Antioxidant: Exhibits free radical scavenging capabilities
• Anticancer: Shows promise in inhibiting various cancer cell lines
• Cardiovascular Protection: Indicates potential in improving vascular health

4. Potential Research Applications

• Hormone-dependent cancer studies
• Menopausal symptom investigations
• Cardiovascular disease research
• Bone health and osteoporosis studies

5. Current Research Focus

Ongoing studies are investigating Formononetin’s effects on:

• Estrogen receptor-mediated signaling pathways
• Cancer cell proliferation and apoptosis mechanisms
• Vascular endothelial function and atherosclerosis
• Bone metabolism and osteoblast activity

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other phytoestrogens

7. Regulatory Considerations

Formononetin (485-72-3) is primarily used in research settings and as a component in some dietary supplements. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for menopausal symptoms and cardiovascular health
• Exploration of Formononetin’s potential in combination cancer therapies
• Investigation of its long-term effects on hormonal balance and bone density

9. Collaborative Opportunities

We invite oncologists, endocrinologists, cardiologists, and academic institutions to explore the research potential of Formononetin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Formononetin – a powerful isoflavone at the forefront of natural product-based therapeutic strategies.