NST Chemicals
  • Home
  • Products
  • Certificate of Anaylysis
  • Blog
  • Contact Us
0 items / €0
Diosmetin CAS 520-34-3
HomeFlavonoids Diosmetin
Previous product
Lanosterol CAS 79-63-0
Lanosterol €90 – €430
Back to products
Next product
Dulcitol CAS 608-66-2
Dulcitol €110 – €540

Diosmetin

€130 – €640

Clear

Synonyms: 3′,5,7-Trihydroxy-4′-methoxyflavone

25 g € 130
50 g € 190
125 g € 350
250 g € 640
For other quantities contact us at sales@nstchemicals.com
Cat. Nr. NST-10-70
CAS 520-34-3
Purity 98% (HPLC)
Appearance Light yellow powder
Molecular formula C16H12O6
Molecular weight 300,26
Storage +2 … +8 °C

Certificate of analysis available by request to sales@nstchemicals.com

SKU: N/A Categories: All products, Flavonoids
  • Description
Description

What is Diosmetin?

Diosmetin is a flavanoid-type compound with a vast variety of biological activities. It can be found in various sources in nature, but are most natural abundance is in citrus plants like lemon, pompia, orange, tangerine, etc.

Diosmetin has been gathering its use as an anticancer agent, however, it has displayed its ability to be an effective treatment for other diseases like:

  • asthma
  • gout
  • cardiovascular disorders
  • cognitive impairment 
  • diabetes
  • tuberculosis
  • and much more.

Diosmetin as an anticancer agent

Medicinal chemists have looked quite extensively to diosmetin as an anticancer agent. It has been employed for the treatment of myeloid leukemia, showed activity against breast, colon, glioma, colorectal, melanoma, and others.

It has been identified that diosmetin can act via various mechanisms to prevent the formation or spread of cancer. Several studies pointed out that in the case of colon, liver cancer cells, diosmetin inhibited cell proliferation. In breast cancer, leukemia, colorectal, and others it induced apoptosis – programmed cell death. Also reduction of cell viability, accumulation of reactive oxygen species, reduction of angiogenesis, and arrest of the cell cycle have been identified.

Some studies have pointed out the positive effect of diosmetin in combination with other anti-cancer drugs. Synergistic effects have been found with paclitaxel in the treatment of lung cancer.

Cardiovascular health improvement with diosmetin

Diosmetin has been studied for its protective effects on our cardiovascular health. Attention has been put on cytoprotective activity on damaged cells caused by myocardial infarct. The use of diosmetin reduced the number of cells where apoptosis was induced. Also, it showed protective effects in ischemic stroke by being involved in several pathways.

Antioxidant activity of diosmetin

Due to their structure, flavonoids have been known for their antioxidative potential. Hydroxyl groups attached to aromatic phenyl moiety are able to neutralize many reactive radicals like reactive oxygen and nitrogen species. 

Diosmetin is able to reduce the damage of reactive oxygen species on cell membranes, increase hydroxide as prooxidant concentration, and scavenge reactive metallic cations. 

Diosmetin as antimicrobial agent

Medicinal chemists have tested natural product extracts containing diosmetin as the main compound against various pathogenic bacteria. They discovered that diosmetin was effective against Streptococcus pneumonia, Klebsiella pneumonia, Staphylococcus aureus and others.

Anti-inflammatory activity

Diosmetin has been identified to decrease inflammations through several metabolic pathways. It was able to reduce the concentration of inflammation mediators like nitric oxide, tumor necrosis factor, and others. 

It was found that diosmetin was an effective treatment against rheumatoid arthritis, neuroinflammation, and neuronal apoptosis, and reduced inflammation in case of acute lung injury.

Improve cognitive impairment

Diosmetin has been evaluated on ethanol-induced cognitive impairment due to anticholinesterase activity. It showed improved spatial memory and even be used in Alzheimer-like cognitive impairment caused by alcohol.

In conclusion

Diosmetin has been studied on several other biological implications, like anti-lipolytic, anti-hemorrhoid, antigout, antiulcer, and gastroprotective activity. This compound has a lot of implications for you to still explore. In order for you to make it easier, visit our store, to acquire high-quality diosmetin now.

Related products

Luteolin CAS 491-70-3
Quick view
Close

Luteolin

€80 – €390
Select options
Quick view
Close

Betulonic acid

€195 – €600
Select options
Dihydromyricetin CAS 27200-12-0
Quick view
Close

Dihydromyricetin

€90 – €450
Select options
Puerarin CAS 3681-99-0
Quick view
Close

Puerarin

€100 – €490
Select options
Nobiletin CAS 478-01-3
Quick view
Close

Nobiletin

€90 – €410
Select options
Baicalein CAS 491-67-8
Quick view
Close

Baicalein

€80 – €390
Select options
Phlorizin CAS 60-81-1
Quick view
Close

Phlorizin

€120 – €570
Select options
Genistin CAS 529-59-9
Quick view
Close

Genistin

€110 – €520
Select options


Have Questions? We are Here to Help You!

Nature Science Technologies is among the world’s leading companies for Betulin derivatives
CONTACT US

INFORMATIONAL LINKS

    • Home
    • About Us
    • Blog
    • Products
    • Projects
    • Privacy Policy
    • Contact Us

CONTACT INFORMATION

Address
Rupnicu 4, Olaine, LV-2114, Latvia

Email Address
sales@nstchemicals.com

Phone Number
+371 24220280

Nature Science Technologies 2021. All Rights Reserved.
Shopping cart
close