Apigenin: Potent Flavonoid for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 4′,5,7-Trihydroxyflavone
• CAS Number: 520-36-5
• Source: Naturally occurring in various fruits and vegetables; also synthetically produced

2. Biochemical Significance

Apigenin is a flavonoid with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential therapeutic properties, making it a compound of significant interest in nutritional and pharmaceutical research.

3. Key Properties of Apigenin

• Antioxidant: Exhibits strong free radical scavenging activity
• Anti-inflammatory: Demonstrates ability to modulate inflammatory pathways
• Anticancer Potential: Shows promise in various cancer models
• Neuroprotective: Indicates potential in protecting neuronal cells

4. Potential Research Applications

• Cancer research and chemoprevention studies
• Neurodegenerative disorder investigations
• Cardiovascular health research
• Anti-aging and skin health studies

5. Current Research Focus

Ongoing studies are investigating Apigenin’s effects on:

• Various cancer types and mechanisms of action
• Inflammatory signaling pathways
• Cognitive function and neuroprotection
• Skin photoprotection and collagen synthesis

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Apigenin (CAS 520-36-5) is generally recognized as safe (GRAS) for use in foods. Its use in specific therapeutic applications may require additional regulatory approval depending on the jurisdiction and intended use.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific health indications
• Exploration of Apigenin’s potential in combination therapies
• Investigation of its epigenetic modulation capabilities

9. Collaborative Opportunities

We invite oncologists, neurologists, dermatologists, and academic institutions to explore the research potential of Apigenin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Apigenin – a versatile flavonoid at the forefront of natural product-based therapeutic strategies.