Fisetin: Potent Flavonoid for Advanced Anti-Aging and Neuroprotective Research

1. Molecular Identity

• Chemical Name: 3,3′,4′,7-Tetrahydroxyflavone
• CAS Number: 528-48-3
• Source: Naturally occurring in various fruits and vegetables, including strawberries, apples, and onions

2. Biochemical Significance

Fisetin is a flavonoid with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential senolytic properties, making it a compound of significant interest in anti-aging research, neuroscience, and oncology studies.

3. Key Properties of Fisetin

• Antioxidant: Exhibits strong free radical scavenging ability
• Anti-inflammatory: Demonstrates potential to modulate inflammatory pathways
• Senolytic: Shows promise in selectively eliminating senescent cells
• Neuroprotective: Indicates efficacy in protecting neuronal cells

4. Potential Research Applications

• Anti-aging and longevity studies
• Neurodegenerative disease investigations
• Cancer research
• Cardiovascular health studies

5. Current Research Focus

Ongoing studies are investigating Fisetin’s effects on:

• Cellular senescence and aging processes
• Neuroprotection mechanisms in various brain disorders
• Cancer cell proliferation and apoptosis
• Oxidative stress and inflammation in cardiovascular diseases

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other anti-aging compounds

7. Regulatory Considerations

Fisetin (CAS 528-48-3) is primarily used in research settings and as a dietary supplement in some countries. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for age-related disorders and neurodegenerative diseases
• Exploration of Fisetin’s potential in combination therapies for cancer
• Investigation of its long-term effects on health span and lifespan

9. Collaborative Opportunities

We invite gerontologists, neuroscientists, oncologists, and academic institutions to explore the research potential of Fisetin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Fisetin – a powerful flavonoid at the forefront of anti-aging and neuroprotective strategies.