Fangchinoline CAS 436-77-1
€240 – €1080
Synonyms: Fangchinoline, Limacine, 7-O-Demethyltetrandrine, Hanfangchin B
Download quality specification Fangchinoline-CAS-436-77-1-QS.pdf
0,5 g | € 240 |
1 g | € 330 |
2,5 g | € 600 |
5 g | € 1080 |
Cat. No. | NST-10-14 |
CAS | 436-77-1 |
Purity | 98% (HPLC) |
Appearance | White powder |
Molecular formula | C37H40N2O6 |
Molecular weight | 608,72 |
Storage | store in freezing or fridge conditions, keep away from strong light and heat |
Certificate of analysis available by request to [email protected]
Fangchinoline: Potent Bisbenzylisoquinoline Alkaloid for Advanced Natural Compound Research
1. Molecular Identity
- Chemical Name: (1S,1’S)-6,6′,12,12′-Tetramethoxy-2,2′-dimethylberbaman
- CAS Number: 436-77-1
- Molecular Formula: C37H40N2O6
- Source: Naturally occurring in Stephania tetrandra
2. Biochemical Significance
Fangchinoline is a bisbenzylisoquinoline alkaloid with a unique molecular scaffold. It is under active investigation for its potential roles in inflammation, cellular regulation, and neurological research models.
3. Key Properties of Fangchinoline
- Inflammation Modulation: In vitro studies show regulatory effects on cytokine pathways
- Cell Regulation: Investigated for impact on cellular proliferation and apoptosis
- Neuronal Models: Evaluated in systems related to neuroprotection
- Vascular Research: Studied in relation to endothelial and smooth muscle cell behavior
4. Potential Research Applications
- Oncology-related cell signaling investigations
- Neuroinflammation and oxidative stress models
- Vascular function and metabolic research
- Studies on bioactive alkaloid mechanisms
5. Current Research Focus
Ongoing studies explore:
- Mechanistic pathways in programmed cell death
- Role in central nervous system inflammation
- Calcium signaling in vascular tissues
- Combinatorial effects with related alkaloids
6. Formulation Challenges and Innovations
Research efforts aim to:
- Improve solubility and experimental delivery
- Enable targeted carrier systems in model systems
- Stabilize in various pH and oxidative environments
7. Bulk Availability and Technical Data
- Purity: ≥98% by HPLC
- Form: Light yellow powder
- Packaging: Research and bulk laboratory scale
- Documentation: COA, MSDS, and full specification sheets available upon request
8. Compliance and Handling
Fangchinoline (CAS 436-77-1) is intended for laboratory research use. All handling should follow institutional guidelines for experimental compounds. Not intended for human or animal consumption.
9. Future Research Directions
Expected developments include:
- In-depth exploration of its bioactivity in inflammation models
- Studies on neuronal function and oxidative pathways
- Further evaluation in multi-compound screening libraries
10. Collaborative Opportunities
We welcome partnerships with researchers in natural compound development, neurobiology, cell biology, and vascular studies. For bulk orders or technical discussions, contact us at [email protected].
Partner with NST Chemicals in exploring Fangchinoline – a structurally distinct bisbenzylisoquinoline alkaloid for next-generation research in inflammation, neurology, and cell regulation.