Fangchinoline CAS 436-77-1

2401080

Synonyms: Fangchinoline, Limacine, 7-O-Demethyltetrandrine, Hanfangchin B

Download quality specification Fangchinoline-CAS-436-77-1-QS.pdf

0,5 g € 240
1 g € 330
2,5 g € 600
5 g € 1080
For bulk quantities contact us at [email protected]
Cat. No. NST-10-14
CAS 436-77-1
Purity 98% (HPLC)
Appearance White powder
Molecular formula C37H40N2O6
Molecular weight 608,72
Storage store in freezing or fridge conditions, keep away from strong light and heat

Certificate of analysis available by request to [email protected]

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Description

Fangchinoline: Potent Bisbenzylisoquinoline Alkaloid for Advanced Natural Compound Research

1. Molecular Identity

  • Chemical Name: (1S,1’S)-6,6′,12,12′-Tetramethoxy-2,2′-dimethylberbaman
  • CAS Number: 436-77-1
  • Molecular Formula: C37H40N2O6
  • Source: Naturally occurring in Stephania tetrandra

2. Biochemical Significance

Fangchinoline is a bisbenzylisoquinoline alkaloid with a unique molecular scaffold. It is under active investigation for its potential roles in inflammation, cellular regulation, and neurological research models.

3. Key Properties of Fangchinoline

  • Inflammation Modulation: In vitro studies show regulatory effects on cytokine pathways
  • Cell Regulation: Investigated for impact on cellular proliferation and apoptosis
  • Neuronal Models: Evaluated in systems related to neuroprotection
  • Vascular Research: Studied in relation to endothelial and smooth muscle cell behavior

4. Potential Research Applications

  • Oncology-related cell signaling investigations
  • Neuroinflammation and oxidative stress models
  • Vascular function and metabolic research
  • Studies on bioactive alkaloid mechanisms

5. Current Research Focus

Ongoing studies explore:

  • Mechanistic pathways in programmed cell death
  • Role in central nervous system inflammation
  • Calcium signaling in vascular tissues
  • Combinatorial effects with related alkaloids

6. Formulation Challenges and Innovations

Research efforts aim to:

  • Improve solubility and experimental delivery
  • Enable targeted carrier systems in model systems
  • Stabilize in various pH and oxidative environments

7. Bulk Availability and Technical Data

  • Purity: ≥98% by HPLC
  • Form: Light yellow powder
  • Packaging: Research and bulk laboratory scale
  • Documentation: COA, MSDS, and full specification sheets available upon request

8. Compliance and Handling

Fangchinoline (CAS 436-77-1) is intended for laboratory research use. All handling should follow institutional guidelines for experimental compounds. Not intended for human or animal consumption.

9. Future Research Directions

Expected developments include:

  • In-depth exploration of its bioactivity in inflammation models
  • Studies on neuronal function and oxidative pathways
  • Further evaluation in multi-compound screening libraries

10. Collaborative Opportunities

We welcome partnerships with researchers in natural compound development, neurobiology, cell biology, and vascular studies. For bulk orders or technical discussions, contact us at [email protected].

Partner with NST Chemicals in exploring Fangchinoline – a structurally distinct bisbenzylisoquinoline alkaloid for next-generation research in inflammation, neurology, and cell regulation.