Epicatechin: Potent Flavonoid for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
• CAS Number: 490-46-0
• Molecular Formula: C15H14O6
• Source: Naturally occurring in various foods, including cocoa, green tea, and certain fruits

2. Biochemical Significance

Epicatechin is a flavonoid belonging to the catechin family with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, cardiovascular protective, and potential neuroprotective properties, making it a compound of significant interest in pharmaceutical research and nutraceutical studies.

3. Key Properties of Epicatechin

• Antioxidant: Exhibits strong free radical scavenging ability
• Cardioprotective: Demonstrates potential to improve cardiovascular health
• Neuroprotective: Shows promise in protecting neuronal cells
• Metabolic Regulator: Indicates efficacy in improving insulin sensitivity

4. Potential Research Applications

• Cardiovascular disease studies
• Neurodegenerative disorder investigations
• Diabetes and metabolic syndrome research
• Exercise performance and muscle function studies

5. Current Research Focus

Ongoing studies are investigating Epicatechin’s effects on:

• Endothelial function and nitric oxide production
• Neuroprotection mechanisms in brain disorders
• Glucose metabolism and insulin signaling pathways
• Mitochondrial biogenesis and muscle performance

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Epicatechin (490-46-0) is primarily used in research settings and as a component in some dietary supplements. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for cardiovascular and neurodegenerative disorders
• Exploration of Epicatechin’s potential in sports nutrition and performance enhancement
• Investigation of its long-term effects on aging and longevity

9. Collaborative Opportunities

We invite cardiologists, neurologists, endocrinologists, and academic institutions to explore the research potential of Epicatechin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Epicatechin – a powerful flavonoid at the forefront of natural product-based therapeutic strategies.