Epigallocatechin: Potent Catechin for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
• CAS Number: 970-74-1
• Molecular Formula: C15H14O7
• Source: Naturally occurring in green tea, white tea, and other plant sources

2. Biochemical Significance

Epigallocatechin is a flavonoid belonging to the catechin family with diverse biological activities. Its unique molecular structure contributes to its potent antioxidant, anti-inflammatory, and potential chemopreventive properties, making it a compound of significant interest in pharmaceutical research and nutraceutical studies.

3. Key Properties of Epigallocatechin

• Antioxidant: Exhibits strong free radical scavenging ability
• Anti-inflammatory: Demonstrates potential to modulate inflammatory pathways
• Chemopreventive: Shows promise in inhibiting various cancer cell lines
• Cardioprotective: Indicates efficacy in improving cardiovascular health

4. Potential Research Applications

• Cancer prevention and treatment studies
• Cardiovascular disease investigations
• Neurodegenerative disorder research
• Metabolic syndrome and diabetes studies

5. Current Research Focus

Ongoing studies are investigating Epigallocatechin’s effects on:

• Cancer cell signaling pathways and apoptosis mechanisms
• Lipid metabolism and atherosclerosis progression
• Neuroprotection in models of various brain disorders
• Glucose homeostasis and insulin sensitivity

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Epigallocatechin (970-74-1) is primarily used in research settings and as a component in some dietary supplements. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for cancer prevention and cardiovascular diseases
• Exploration of Epigallocatechin’s potential in combination therapies
• Investigation of its long-term effects on health and disease prevention

9. Collaborative Opportunities

We invite oncologists, cardiologists, neurologists, and academic institutions to explore the research potential of Epigallocatechin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Epigallocatechin – a powerful catechin at the forefront of natural product-based therapeutic strategies.