Limonin: High-Purity Limonoid for Advanced Natural Product Research

1. Molecular Identity

• Chemical Name: (4R,4aS,6aR,7R,8S,10R,11S)-7-Hydroxy-3,7,11-trimethyl-13-oxo-4,4a,5,6,6a,7,8,9,10,11,12,13b-dodecahydro-4,8-methanobenzo[2,3]cyclobutyl[3,4]cyclopenta[1,2-c]pyran-1-carboxylic acid
• CAS Number: 1180-71-8
• Molecular Formula: C₂₆H₃₀O₈
• Source: Naturally found in citrus fruit seeds and peels

2. Biochemical Significance

Limonin is a triterpenoid limonoid studied for its unique chemical structure and relevance to natural antioxidant and inflammation-modulating mechanisms. It plays a key role in citrus phytochemistry and is widely used in food, health, and natural product research.

3. Key Research-Relevant Properties

• Oxidative Response: Investigated for radical scavenging and redox activity
• Inflammation Modulation: Explored for effects on cytokine and signaling responses
• Microbial Interaction: Studied for effects on bacterial viability
• Natural Phytochemical Marker: Useful in citrus quality and processing studies

4. Potential Research Applications

• Antioxidant and free radical studies
• Research on inflammation pathways and metabolic markers
• Citrus biochemistry and functional food development
• Natural preservation and antimicrobial compound screening

5. Current Research Focus

Current scientific investigations focus on:

• Redox modulation in cell-based assays
• Enzyme activity related to oxidative balance
• Evaluation of bacterial response mechanisms
• Synergistic effects with other citrus-derived compounds

6. Formulation Challenges and Innovations

Researchers are actively developing:

• Solubility-enhancing formulations for analytical use
• Stabilized forms for natural product testing
• Multi-compound delivery systems with phytochemical synergy

7. Bulk Availability and Specifications

• Purity: ≥98% (HPLC)
• Form: Off-white to pale yellow powder
• Availability: Offered in research and bulk quantities
• Documentation: COA, MSDS, and analytical data available

8. Handling and Intended Use

Limonin (CAS 1180-71-8) is intended exclusively for laboratory use, quality control, and industrial R&D. Not for food, cosmetic, or clinical use. Use appropriate protective equipment and follow standard lab procedures.

9. Future Research Directions

Emerging research topics include:

• Advanced formulation systems for limonoid stabilization
• Combined antioxidant and anti-inflammatory effect analysis
• Exploration of citrus phytochemicals in food systems

10. Collaborative Opportunities

We invite food scientists, biochemists, microbiologists, and academic researchers to explore Limonin’s potential. For bulk orders, quotations, or research inquiries, please contact us at [email protected].

Advance your natural compound research with Limonin – a high-purity citrus limonoid for innovative scientific applications.