Valencene: Versatile Sesquiterpene for Fragrance and Bioactive Research

1. Molecular Identity

• Chemical Name: (4aS,5S)-4a,5-Dimethyl-3-(prop-1-en-2-yl)-1,2,3,4,4a,5,6,7-octahydronaphthalene
• CAS Number: 4630-07-3
• Source: Naturally occurring in Valencia oranges and other citrus fruits, also produced biotechnologically

2. Biochemical Significance

Valencene is a sesquiterpene hydrocarbon with a characteristic citrus aroma. Its unique molecular structure contributes to its olfactory properties and potential bioactivities, making it a compound of interest in fragrance chemistry, food science, and natural product research.

3. Key Properties

• Aromatic Profile: Provides a distinctive citrus and woody scent
• Precursor Compound: Can be oxidized to produce nootkatone, a high-value aroma compound
• Potential Bioactivity: Shows promise in various biological applications
• Natural Origin: Offers a sustainable alternative to synthetic fragrances

4. Potential Research Applications

• Fragrance and flavor development
• Insect repellent studies
• Anticancer and anti-inflammatory investigations
• Biotechnological production optimization

5. Current Research Focus

Ongoing studies are investigating Valencene’s potential in:

• Development of natural insect repellents
• Exploration of antimicrobial properties
• Enhancement of biotechnological production methods
• Investigation of potential health benefits

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Improving stability in various product formulations
• Developing encapsulation techniques for controlled release
• Optimizing extraction and purification methods

7. Regulatory Considerations

Valencene (CAS 4630-07-3) is Generally Recognized as Safe (GRAS) by the FDA for use as a flavoring substance. Its use in fragrances and other applications is subject to regional regulatory guidelines.

8. Future Research Directions

The scientific community anticipates:

• Advanced studies on valencene’s biological activities
• Development of novel valencene derivatives
• Exploration of sustainable production methods

9. Collaborative Opportunities

We invite fragrance chemists, food scientists, natural product researchers, and academic institutions to explore the research potential of Valencene. For inquiries, collaborations, or to discuss how Valencene can benefit your research projects, please contact us at [email protected].

Join us in unlocking the full potential of Valencene – a versatile sesquiterpene bridging the worlds of fragrance chemistry and bioactive research.