Cardiovascular Protection with Natural Compounds

The main cause of death throughout the world is cardiovascular diseases – especially myocardial infarctions more commonly known as heart attacks. Therefore, the use of natural compounds like antioxidants, phytoestrogens, etc. has been extensively studied for their protective effects on cardiovascular systems. Keep on reading to learn more about such natural compounds.

Natural Compounds for Myocardial Regeneration

Myocardial infarction is one of the major causes of mortality throughout America, Asia, and Europe. In the case of myocardial infarction, typically irreversible cell death happens. Damaged tissue can dramatically increase the chance of heart failure. Although modern therapeutic options have come with great ways to improve the symptoms and decelerate the continuous dying of cells, there are no ways to regenerate these cells.

Stem cell therapy has been quite extensively studied for such events and many natural compounds of plant extracts have exhibited the ability to trigger, selectively control and differentiate these cells.

Such natural compounds like:

have been studied for this purpose.

Embryonic stem cells have been studied the most extensively for such a goal. From preliminary studies on different animal models, these embryonic stem cells have shown great ability to differentiate to form selective tissue. However, a lot of countries have overruled the use of these stem cells due to possible immune rejection and moral reasons.

Also, other sources of stem cells have been used like: induced pluripotent, bone marrow, mesenchymal and cardiac stem cells. 

This is especially promising, as our cardiovascular system contains cardiac stem cells and activation of these cells by the natural compound is a promising field of medicine and pharmacy.

The mechanism of action is as follows: after the injection of stem cells into the heart, they allocate a hostile microenvironment that is characterized by reduced blood supply, deprivation of nutrients, and heightened concentration of cytokines like TNF-α and IL-6. Then the treatment of various natural compounds can actually stimulate cell survival, proliferation, and differentiation leading to cardiac repair.

Cardiovascular Protection with Natural Compounds

Interestingly, compounds like lupinine, resveratrol, curcumin, and others have shown the ability to even counteract the effects of infarction relieving symptoms and reducing cell damage.

Many of these compounds exhibit the ability to protect against free-radical-induced peroxidation and other antioxidative properties. Also, on a cellular level, natural compounds were able to counteract processes leading to cell death-like apoptosis, interacting with mitochondria regulating membrane potential, and more.

Same antioxidative properties can lead to protection against atherosclerosis as these compounds can counteract the oxidation of healthy lipids like low-density lipoproteins, cholesterol, and more.

Effects of ginseng have been studied on rat models. It was found that extract was able to counteract electrocardiogram abnormalities and changes in left ventricular systolic pressure.

Effects of curcumin have also been extensively studied. Several studies have identified curcumin’s ability to counteract many cardiovascular pathologies like aortic aneurysm, cardiac hypertrophy, cardiotoxicity, and diabetic complications.

In conclusion

Natural compounds have a lot of promise for the protection of our cardiovascular system. Research has shown the ability to reduce various symptoms that could lead to a fatal outcome, like atherosclerosis, preventing cell death, and more. Natural compounds even exhibit a high potential to help regenerate damaged tissue. If you wish to continue in this field of research, visit our store to buy high-quality natural compounds.