3-Oxooleanolic Acid: Advanced Triterpenoid for Biomedical Research

1. Molecular Identity

• Chemical Name: 3-Oxoolean-12-en-28-oic acid
• CAS Number: 17990-42-0
• Source: Derivative of oleanolic acid, found in various plant species or synthetically produced

2. Biochemical Significance

3-Oxooleanolic acid is a triterpenoid compound derived from oleanolic acid. Its unique molecular structure, featuring a ketone group at the C-3 position, contributes to its diverse biological activities, making it a compound of significant interest in natural product research and potential therapeutic applications.

3. Key Properties

• Anti-inflammatory: Demonstrates potential in modulating inflammatory responses
• Antioxidant: Exhibits free radical scavenging capabilities
• Anticancer Potential: Shows promise in various cancer models
• Hepatoprotective: Indicates liver-protecting properties

4. Potential Research Applications

• Cancer research and drug development
• Inflammatory disorder studies
• Liver disease investigations
• Antioxidant and free radical research

5. Current Research Focus

Ongoing studies are investigating 3-Oxooleanolic acid’s effects on:

• Various cancer types and mechanisms of action
• Inflammatory signaling pathways
• Liver fibrosis and hepatotoxicity
• Oxidative stress-induced cellular damage

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability and solubility
• Developing targeted delivery systems for improved efficacy
• Creating semi-synthetic derivatives with optimized properties

7. Regulatory Considerations

As a research compound, 3-Oxooleanolic acid (CAS 17990-42-0) is primarily used in preclinical studies. Its development for therapeutic applications would require extensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced studies on the molecular mechanisms of 3-Oxooleanolic acid’s biological activities
• Exploration of its potential in combination therapies
• Investigation of structure-activity relationships for optimized derivatives

9. Collaborative Opportunities

We invite cancer researchers, pharmacologists, natural product scientists, and academic institutions to explore the research potential of 3-Oxooleanolic acid. For inquiries, collaborations, or to discuss how 3-Oxooleanolic acid can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with 3-Oxooleanolic acid – a promising triterpenoid at the intersection of natural product chemistry and innovative therapeutic strategies.