3-Oxooleanolic Acid: Advanced Triterpenoid for Biomedical Research
1. Molecular Identity
- Chemical Name: 3-Oxoolean-12-en-28-oic acid
- CAS Number: 17990-42-0
- Source: Derivative of oleanolic acid, found in various plant species or synthetically produced
2. Biochemical Significance
3-Oxooleanolic acid is a triterpenoid compound derived from oleanolic acid. Its unique molecular structure, featuring a ketone group at the C-3 position, contributes to its diverse biological activities, making it a compound of significant interest in natural product research and potential therapeutic applications.
3. Key Properties
- Anti-inflammatory: Demonstrates potential in modulating inflammatory responses
- Antioxidant: Exhibits free radical scavenging capabilities
- Anticancer Potential: Shows promise in various cancer models
- Hepatoprotective: Indicates liver-protecting properties
4. Potential Research Applications
- Cancer research and drug development
- Inflammatory disorder studies
- Liver disease investigations
- Antioxidant and free radical research
5. Current Research Focus
Ongoing studies are investigating 3-Oxooleanolic acid’s effects on:
- Various cancer types and mechanisms of action
- Inflammatory signaling pathways
- Liver fibrosis and hepatotoxicity
- Oxidative stress-induced cellular damage
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing bioavailability and solubility
- Developing targeted delivery systems for improved efficacy
- Creating semi-synthetic derivatives with optimized properties
7. Regulatory Considerations
As a research compound, 3-Oxooleanolic acid is primarily used in preclinical studies. Its development for therapeutic applications would require extensive safety and efficacy evaluations to meet regulatory standards.
8. Future Research Directions
The scientific community anticipates:
- Advanced studies on the molecular mechanisms of 3-Oxooleanolic acid’s biological activities
- Exploration of its potential in combination therapies
- Investigation of structure-activity relationships for optimized derivatives
9. Collaborative Opportunities
We invite cancer researchers, pharmacologists, natural product scientists, and academic institutions to explore the research potential of 3-Oxooleanolic acid. For inquiries, collaborations, or to discuss how 3-Oxooleanolic acid can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing biomedical research with 3-Oxooleanolic acid – a promising triterpenoid at the intersection of natural product chemistry and innovative therapeutic strategies.