Lutein: Essential Carotenoid for Advanced Ocular and Antioxidant Research

1. Molecular Identity

• Chemical Name: β,ε-Carotene-3,3′-diol
• CAS Number: 127-40-2
• Source: Naturally occurring in green leafy vegetables, marigold flowers, and egg yolks

2. Biochemical Significance

Lutein is a xanthophyll carotenoid with crucial roles in eye health and antioxidant defense. Its unique molecular structure allows it to accumulate in the macula of the eye, making it a compound of significant interest in ophthalmological and nutritional research.

3. Key Properties of Lutein

• Macular Pigment: Concentrates in the macula, protecting against harmful light
• Antioxidant: Exhibits potent free radical scavenging activity
• Blue Light Filter: Absorbs damaging blue light wavelengths
• Skin Protection: Demonstrates potential in photoprotection

4. Potential Research Applications

• Age-related macular degeneration (AMD) studies
• Cataract research
• Cognitive function investigations
• Skin health and anti-aging studies

5. Current Research Focus

Ongoing studies are investigating lutein’s effects on:

• Macular pigment optical density and visual performance
• Oxidative stress in ocular tissues
• Cognitive function and brain health
• Systemic inflammation and cardiovascular health

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other eye health nutrients

7. Regulatory Considerations

Lutein (CAS 127-40-2) is Generally Recognized as Safe (GRAS) by the FDA for use in foods and dietary supplements. Specific health claims may require additional regulatory approval depending on the jurisdiction.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific ocular indications
• Exploration of lutein’s role in neuroprotection
• Investigation of its potential in personalized nutrition approaches

9. Collaborative Opportunities

We invite ophthalmologists, nutritionists, neuroscientists, and academic institutions to explore the research potential of lutein. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing ocular and antioxidant research with lutein – a key carotenoid at the forefront of eye health and anti-aging studies.