Paeonol : Versatile Natural Phenolic Compound for Advanced Biomedical Research

1. Molecular Identity

• Chemical Name: 2′-Hydroxy-4′-methoxyacetophenone
• CAS Number: 552-41-0
• Source: Naturally occurring in Paeonia species and Cynanchum paniculatum

2. Biochemical Significance

Paeonol is a phenolic compound with diverse biological activities. Its unique molecular structure contributes to its potent anti-inflammatory, antioxidant, and potential neuroprotective properties, making it a compound of significant interest in pharmaceutical research and traditional medicine studies.

3. Key Properties of Paeonol

• Anti-inflammatory: Exhibits strong ability to modulate inflammatory responses
• Antioxidant: Demonstrates potent free radical scavenging capabilities
• Neuroprotective: Shows promise in protecting neuronal cells
• Cardiovascular Protection: Indicates efficacy in improving cardiovascular health

4. Potential Research Applications

• Inflammatory disorder studies
• Neurodegenerative disease investigations
• Cardiovascular research
• Cancer and cell proliferation studies

5. Current Research Focus

Ongoing studies are investigating Paeonol’s effects on:

• Inflammatory signaling pathways in various tissues
• Oxidative stress markers and antioxidant enzymes
• Neuroprotection mechanisms in brain disorders
• Cardiovascular function and atherosclerosis

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Paeonol (CAS 552-41-0) is primarily used in research settings and traditional medicine. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for inflammatory and neurodegenerative disorders
• Exploration of Paeonol’s potential in combination therapies
• Investigation of its mechanisms of action at the molecular level

9. Collaborative Opportunities

We invite neurologists, cardiologists, immunologists, and academic institutions to explore the research potential of Paeonol. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Paeonol – a versatile natural phenolic compound at the forefront of innovative therapeutic strategies.