Synephrine: Potent Adrenergic Amine for Advanced Metabolic Research

1. Molecular Identity

• Chemical Name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol
• CAS Number: 94-07-5
• Source: Naturally occurring in various citrus fruits, especially bitter orange (Citrus aurantium)

2. Biochemical Significance

Synephrine is an adrenergic amine with diverse pharmacological activities. Its structural similarity to ephedrine contributes to its potential thermogenic, lipolytic, and bronchodilatory properties, making it a compound of significant interest in metabolic research and sports nutrition studies.

3. Key Properties of Synephrine

• Thermogenic: Demonstrates ability to increase metabolic rate and energy expenditure
• Lipolytic: Shows potential in promoting fat breakdown
• Bronchodilatory: Exhibits promise in relaxing bronchial smooth muscles
• Appetite Suppressant: Indicates efficacy in reducing food intake

4. Potential Research Applications

• Obesity and weight management studies
• Metabolic disorder investigations
• Sports performance research
• Respiratory function studies

5. Current Research Focus

Ongoing studies are investigating Synephrine’s effects on:

• Metabolic pathways related to energy expenditure
• Adipose tissue lipolysis mechanisms
• Adrenergic receptor interactions
• Potential synergistic effects with other thermogenic compounds

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing stable formulations for various applications
• Creating synergistic combinations with other metabolic enhancers

7. Regulatory Considerations

Synephrine (CAS 94-07-5) is used in research settings and as a component in some dietary supplements. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for weight management and metabolic disorders
• Exploration of Synephrine’s potential in combination therapies
• Investigation of its long-term effects on metabolic health

9. Collaborative Opportunities

We invite nutritionists, endocrinologists, sports medicine researchers, and academic institutions to explore the research potential of Synephrine. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing biomedical research with Synephrine – a potent adrenergic amine at the forefront of metabolic and sports nutrition research strategies.