Betaine Anhydrous: Versatile Osmolyte and Methyl Donor

1. Molecular Identity

• Chemical Name: 2-(Trimethylammonio)acetate
• CAS Number: 107-43-7
• Source: Synthesized or extracted from sugar beets and other plant sources

2. Biochemical Significance

Betaine anhydrous, also known as trimethylglycine, is a zwitterionic quaternary ammonium compound. Its role as an osmolyte and methyl donor makes it a compound of significant interest in various fields of biological research, nutrition, and pharmaceutical applications.

3. Key Properties

• Osmolyte: Protects cells against osmotic stress
• Methyl Donor: Participates in one-carbon metabolism
• Hepatoprotective: Supports liver function and health
• Protein Stabilizer: Enhances protein and enzyme stability

4. Potential Research Applications

• Nutritional supplement studies
• Liver disease and metabolic disorder research
• Protein and enzyme stabilization investigations
• Osmotic stress response studies

5. Current Research Focus

Ongoing studies are investigating Betaine anhydrous’s effects on:

• Homocysteine metabolism and cardiovascular health
• Non-alcoholic fatty liver disease (NAFLD)
• Athletic performance and muscle protein synthesis
• Epigenetic regulation through DNA methylation

6. Formulation Challenges and Innovations

Researchers and formulators are actively working on:

• Developing stable formulations for various applications
• Creating synergistic combinations with other nutrients
• Optimizing dosage forms for enhanced bioavailability

7. Regulatory Considerations

Betaine anhydrous CAS 107-43-7 is Generally Recognized as Safe (GRAS) by the FDA for use in dietary supplements and food applications. Its use in specific therapeutic applications may require additional regulatory approval depending on the jurisdiction and intended use.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific health indications
• Exploration of betaine’s role in gut microbiome modulation
• Investigation of potential neuroprotective effects

9. Collaborative Opportunities

We invite researchers, nutritionists, pharmaceutical companies, and academic institutions to explore the research potential of Betaine anhydrous. For inquiries, collaborations, or to discuss how Betaine anhydrous can benefit your research or product development, please contact us at [email protected].

Join us in unlocking the full potential of Betaine anhydrous – a versatile compound bridging nutritional science, biochemistry, and pharmaceutical research.