Cephalotaxine: Research-Grade Alkaloid for Bioactivity Studies

1. Molecular Identity

• Chemical Name: (1S,2R,4R,5R,6R,7S)-5-(3-Hydroxy-4-methoxyphenyl)-1-methyl-4,6-epoxy-2-hydroxymethyl-3-oxabicyclo[3.2.2]nonan-7-ol
• CAS Number: 24316-19-6
• Source: Isolated from species of the Cephalotaxus genus, including Cephalotaxus harringtonia

2. Biochemical and Technical Significance

Cephalotaxine is a structurally distinct alkaloid featuring a pentacyclic framework. It has been widely studied for its interaction with cellular protein synthesis and is a subject of interest in structure–activity relationship (SAR) research within natural products chemistry.

3. Key Characteristics

• Ribosome interaction: Investigated for its ability to modulate protein biosynthesis in vitro
• Lead scaffold: Used in SAR studies for semi-synthetic alkaloid analogues
• Plant-derived molecule: Originates from sustainable botanical sources
• Model compound: Applied in exploratory bioactivity assays

4. Application Areas

• Academic and industrial studies on protein synthesis regulation
• Cellular metabolism investigations
• Exploratory research in bioactive alkaloid libraries
• Preformulation and analytical development of natural compounds

5. Current Research Topics

Active research on Cephalotaxine includes:

• Cellular uptake and solubility profiling
• Structure–activity relationships and molecular modifications
• Resistance profiling in challenging model systems
• Stability under physiological and formulation conditions

6. Bulk Availability and Specifications

• Form: Solid powder (≥98% purity, HPLC verified)
• Use: For laboratory research only — not for medical or human use
• Supply: Bulk quantities available for academic or industrial R&D
• Documentation: COA, MSDS, and technical data provided on request

7. Handling and Regulatory Status

Cephalotaxine (CAS 24316-19-6) is supplied for research purposes only. Appropriate safety protocols should be followed when working with alkaloids. This product is not intended for consumer use.

8. Scientific Outlook

Future directions for Cephalotaxine include:

• Optimization of derivative libraries for enhanced performance in model systems
• Studies into sustainable sourcing via biosynthetic or plant cell culture methods
• Collaborative development of advanced analytical methods

9. Collaboration and Contact

NST Chemicals provides Cephalotaxine in bulk for research and technical development. To request pricing, documentation, or collaboration details, please contact us at [email protected].

Advance your alkaloid research with Cephalotaxine – a distinct scaffold molecule for bioactive compound development and analytical innovation.