Hederagenin: Exploring the Potential of a Natural Triterpenoid

1. Molecular Identity

• Chemical Name: (3β,4α)-3,23-Dihydroxyolean-12-en-28-oic acid
• CAS Number: 465-99-6
• Source: Found in Hedera helix (common ivy) and Sapindus species

2. Biochemical and Technical Significance

Hederagenin is a naturally occurring pentacyclic triterpenoid with diverse physicochemical properties. It plays a key role in natural product chemistry and is used as a scaffold in the development of saponin-based compounds for research and industrial applications.

3. Key Characteristics

• Anti-inflammatory potential: Modulates key biochemical markers
• Fungal resistance support: Shows in vitro activity against certain strains
• Liver model studies: Investigated for hepatocyte stability effects
• Natural compound precursor: Commonly used in saponin synthesis research

4. Research and Industrial Applications

• Natural product and triterpenoid pathway studies
• In vitro inflammation and oxidative stress models
• Botanical extract standardization
• Technical and academic R&D applications

5. Current Research Focus

Ongoing investigations explore:

• Structure-activity relationships and semi-synthetic analogues
• Model systems for liver cell support and oxidative response
• Antifungal screening in laboratory conditions
• Plant defense and triterpenoid biosynthesis pathways

6. Bulk Availability and Technical Data

• Form: Powder (technical grade)
• Purity: ≥98% (HPLC)
• Use: For research and industrial use only
• Supply: Bulk quantities available upon request

7. Regulatory and Handling Notes

Hederagenin (CAS 465-99-6) is provided as a raw material intended for laboratory and technical applications. It is not intended for pharmaceutical, cosmetic, or food use.

8. Future Research Outlook

Areas of interest include:

• Natural saponin derivative development
• Interactions with cellular membranes in vitro
• Use in advanced delivery system materials

9. Collaboration and Bulk Inquiries

We support academic labs, research institutes, and industrial partners with high-quality Hederagenin. For specifications, quotes, or bulk orders, contact us at [email protected].

Unlock the research value of Hederagenin – a key triterpenoid compound bridging natural origin and technical innovation.