Linarin: Exploring the Potential of a Flavonoid Glycoside

1. Molecular Identity

• Chemical Name: Acacetin 7-O-β-D-rutinoside
• CAS Number: 480-36-4
• Source: Found in various plants, notably Chrysanthemum and Linaria species

2. Biochemical Significance

Linarin is a flavonoid glycoside with a unique molecular structure that contributes to its diverse biological activities. Its ability to interact with various cellular targets makes it a compound of significant interest in natural product research and potential therapeutic applications.

3. Key Therapeutic Properties

• Anti-inflammatory: Demonstrates potential in modulating inflammatory responses
• Antioxidant: Exhibits strong free radical scavenging activity
• Neuroprotective: Shows promise in protecting neuronal cells
• Anxiolytic: Demonstrates potential anxiety-reducing effects

4. Potential Applications

• Inflammatory disorder research
• Neurodegenerative disease studies
• Anxiety and mood disorder investigations
• Antioxidant-based therapies

5. Current Research Focus

Ongoing studies are investigating Linarin’s effects on:

• Various inflammatory pathways and related disorders
• Neuroprotection in conditions like Alzheimer’s and Parkinson’s diseases
• Anxiety and stress-related behaviors in preclinical models
• Oxidative stress-induced cellular damage

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing targeted formulations for specific tissues, particularly the brain
• Creating stable preparations for various research applications

7. Regulatory Considerations

As a naturally derived compound, Linarin’s (CAS 480-36-4) regulatory status is evolving. Ongoing research aims to establish its safety profile and efficacy for potential therapeutic applications.

8. Future Directions

The scientific community anticipates:

• Advanced clinical trials for specific indications, particularly in neurology and psychiatry
• Exploration of synergistic effects with other natural compounds
• Development of semi-synthetic derivatives with enhanced properties

9. Collaborative Opportunities

We invite researchers, pharmaceutical companies, and academic institutions to explore the research potential of Linarin. For inquiries, collaborations, or to discuss how Linarin can benefit your research projects, please contact us at [email protected].

Join us in unlocking the potential of Linarin – a promising flavonoid glycoside at the forefront of natural product research and innovative therapeutic strategies.