Vinpocetine: Potent Nootropic for Advanced Neuropharmacological Research

1. Molecular Identity

• Chemical Name: Ethyl (3α,16α)-eburnamenine-14-carboxylate
• CAS Number: 42971-09-5
• Source: Semi-synthetic derivative of vincamine, an alkaloid from Vinca minor

2. Biochemical Significance

Vinpocetine is a synthetic derivative with significant effects on cerebral metabolism and cognitive function. Its unique molecular structure contributes to its neuroprotective and vasodilatory properties, making it a compound of considerable interest in neuropharmacological research.

3. Key Properties of Vinpocetine

• Cerebral Vasodilator: Enhances blood flow to the brain
• Neuroprotective: Demonstrates potential in protecting neuronal cells
• Cognitive Enhancer: Shows promise in improving memory and cognitive function
• Antioxidant: Exhibits free radical scavenging activity in neural tissues

4. Potential Research Applications

• Cognitive disorder studies
• Cerebrovascular disease investigations
• Tinnitus and vertigo research
• Neuroprotection in ischemic events

5. Current Research Focus

Ongoing studies are investigating vinpocetine’s effects on:

• Age-related cognitive decline
• Cerebral circulation disorders
• Neurodegenerative diseases
• Synaptic plasticity and long-term potentiation

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability and blood-brain barrier penetration
• Developing sustained-release formulations
• Creating novel drug delivery systems for targeted cerebral action

7. Regulatory Considerations

Vinpocetine (CAS 42971-09-5) is approved as a prescription drug in several countries for cerebrovascular disorders. Its regulatory status varies globally, and its use in research and potential new therapeutic applications may require additional approval depending on the jurisdiction.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for specific neurological indications
• Exploration of vinpocetine’s potential in combination therapies
• Investigation of long-term effects on brain health and cognition

9. Collaborative Opportunities

We invite neuropharmacologists, cognitive scientists, and academic institutions to explore the research potential of vinpocetine. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at [email protected].

Join us in advancing neuropharmacological research with vinpocetine – a powerful nootropic at the forefront of cognitive enhancement and neuroprotection studies.