Quinic Acid: Versatile Natural Compound for Diverse Research Applications

1. Molecular Identity

• Chemical Name: (1S,3R,4S,5R)-1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid
• CAS Number: 77-95-2
• Source: Naturally occurring in various plants, particularly in coffee beans and cinchona bark

2. Biochemical Significance

Quinic acid is a cyclic polyol carboxylic acid that plays a significant role in plant biochemistry. Its unique structure and biological activities make it a compound of interest in various fields, including natural product chemistry, pharmaceutical research, and food science.

3. Key Properties

• Antioxidant Precursor: Metabolized to form powerful antioxidants in the body
• Choleretic Effect: Potential to stimulate bile production
• Metabolic Intermediate: Involved in the shikimate pathway in plants
• Bioavailability Enhancer: May improve absorption of certain compounds

4. Potential Research Applications

• Antioxidant and free radical research
• Liver health and metabolism studies
• Plant biochemistry investigations
• Pharmaceutical formulation development

5. Current Research Focus

Ongoing studies are investigating Quinic acid’s role in:

• Enhancing bioavailability of pharmaceutical compounds
• Potential anti-inflammatory and neuroprotective effects
• Metabolic profiling of plants and food products
• Development of functional foods and nutraceuticals

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Developing stable formulations for various applications
• Creating quinic acid derivatives with enhanced properties
• Optimizing extraction methods from natural sources

7. Regulatory Considerations

Quinic acid (CAS 77-95-2) is Generally Recognized as Safe (GRAS) by the FDA for use as a flavoring substance. Its use in specific therapeutic applications may require additional regulatory approval depending on the jurisdiction and intended use.

8. Future Research Directions

The scientific community anticipates:

• Advanced studies on quinic acid’s role in human metabolism
• Exploration of its potential in drug delivery systems
• Investigation of quinic acid-based polymers for various applications

9. Collaborative Opportunities

We invite natural product chemists, pharmaceutical researchers, food scientists, and academic institutions to explore the research potential of Quinic acid. For inquiries, collaborations, or to discuss how Quinic acid can benefit your research projects, please contact us at sales@nstchemicals.com.

Join us in unlocking the full potential of Quinic acid – a versatile natural compound bridging plant biochemistry, pharmaceutical research, and food science.