Gastrodin: Potent Natural Phenolic Glycoside for Advanced Neuroscience Research

1. Molecular Identity

• Chemical Name: 4-Hydroxybenzyl alcohol 4-O-β-D-glucopyranoside
• CAS Number: 62499-27-8
• Molecular Formula: C13H18O7
• Source: Naturally occurring in the rhizome of Gastrodia elata, a traditional Chinese medicinal herb

2. Biochemical Significance

Gastrodin is a phenolic glycoside with diverse neurological activities. Its unique molecular structure contributes to its potential neuroprotective, anxiolytic, and cognitive-enhancing properties, making it a compound of significant interest in neuropharmacological research and traditional medicine studies.

3. Key Properties of Gastrodin

• Neuroprotective: Exhibits ability to protect neuronal cells from various insults
• Anxiolytic: Demonstrates potential in reducing anxiety-like behaviors
• Cognitive Enhancer: Shows promise in improving memory and learning
• Antioxidant: Indicates efficacy in reducing oxidative stress in neural tissues

4. Potential Research Applications

• Neurodegenerative disorder studies (e.g., Alzheimer’s, Parkinson’s)
• Anxiety and mood disorder investigations
• Cognitive enhancement research
• Cerebrovascular disease studies

5. Current Research Focus

Ongoing studies are investigating Gastrodin’s effects on:

• Neurotransmitter systems, particularly GABAergic and glutamatergic pathways
• Neuroinflammatory processes in various brain disorders
• Synaptic plasticity and long-term potentiation
• Cerebral blood flow and vascular function

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing blood-brain barrier penetration through novel delivery systems
• Developing stable formulations for various neurological applications
• Creating synergistic combinations with other neuroprotective compounds

7. Regulatory Considerations

Gastrodin (CAS 62499-27-8) is primarily used in research settings and traditional medicine. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for neurodegenerative and anxiety disorders
• Exploration of Gastrodin’s potential in combination therapies for brain health
• Investigation of its long-term effects on cognitive function and neuroprotection

9. Collaborative Opportunities

We invite neurologists, psychiatrists, pharmacologists, and academic institutions to explore the research potential of Gastrodin. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.

Join us in advancing neuroscience research with Gastrodin – a powerful natural phenolic glycoside at the forefront of neuroprotective and cognitive enhancement strategies.