L-Theanine: Natural Amino Acid for Cognitive and Relaxation Research
1. Molecular Identity
- Chemical Name: (2S)-2-Amino-5-(ethylamino)-5-oxopentanoic acid
- CAS Number: 3081-61-6
- Source: Naturally occurring in tea leaves (Camellia sinensis), also synthetically produced
2. Biochemical Significance
L-Theanine is a unique amino acid that structurally resembles glutamate. Its ability to cross the blood-brain barrier and influence neurotransmitter activity makes it a compound of significant interest in neuroscience, cognitive enhancement, and stress reduction research.
3. Key Properties
- Anxiolytic: Promotes relaxation without sedation
- Cognitive Enhancer: May improve attention and cognitive performance
- Neuroprotective: Demonstrates potential in protecting neuronal cells
- Synergistic with Caffeine: Modulates caffeine’s stimulant effects
4. Potential Research Applications
- Stress and anxiety reduction studies
- Cognitive performance and attention research
- Sleep quality investigations
- Neurodegenerative disease studies
5. Current Research Focus
Ongoing studies are investigating L-Theanine’s effects on:
- Stress-related biomarkers and physiological responses
- Attention, memory, and learning processes
- Sleep onset latency and quality
- Neuroprotection mechanisms in various brain disorders
6. Formulation Challenges and Innovations
Researchers are actively working on:
- Enhancing bioavailability and brain penetration
- Developing synergistic combinations with other nootropics
- Creating sustained-release formulations for prolonged effects
7. Regulatory Considerations
L-Theanine (CAS 3081-61-6) is Generally Recognized as Safe (GRAS) by the FDA. Its use in dietary supplements is widespread, but specific health claims may require additional regulatory approval depending on the jurisdiction.
8. Future Research Directions
The scientific community anticipates:
- Advanced clinical trials for anxiety and stress-related disorders
- Exploration of L-Theanine’s potential in combination therapies for cognitive enhancement
- Investigation of long-term effects on brain health and cognitive aging
9. Collaborative Opportunities
We invite neuroscientists, psychologists, nutritional researchers, and academic institutions to explore the research potential of L-Theanine. For inquiries, collaborations, or to discuss how L-Theanine can benefit your research projects, please contact us at sales@nstchemicals.com.
Join us in advancing cognitive and relaxation research with L-Theanine – a natural amino acid at the forefront of understanding mental well-being and cognitive enhancement.
