Rutaecarpine: Potent Alkaloid for Advanced Cardiovascular and Metabolic Research

1. Molecular Identity

• Chemical Name: 1,2,3,9,10,12b-Hexahydro-2-[1-(1H-indol-3-yl)propan-2-yl]-8,9-dimethoxybenzo[a]phenanthridin-5(6H)-one
• CAS Number: 84-26-4
• Source: Naturally occurring in Evodia rutaecarpa and other plants of the Rutaceae family

2. Biochemical Significance

Rutaecarpine is a unique indoloquinazoline alkaloid with diverse pharmacological activities. Its complex molecular structure contributes to its potential cardiovascular, anti-inflammatory, and metabolic properties, making it a compound of significant interest in pharmaceutical research and traditional medicine studies.

3. Key Properties of Rutaecarpine

• Cardiovascular Modulator: Demonstrates ability to influence blood pressure and heart rate
• Anti-inflammatory: Shows potential in modulating inflammatory pathways
• Thermogenic: Exhibits promise in increasing body temperature and metabolism
• Analgesic: Indicates efficacy in pain management

4. Potential Research Applications

• Cardiovascular disease studies
• Metabolic disorder investigations
• Pain management research
• Thermoregulation and energy expenditure studies

5. Current Research Focus

Ongoing studies are investigating Rutaecarpine’s effects on:

• Mechanisms of action in cardiovascular regulation
• Inflammatory signaling pathways in various tissues
• Metabolic pathways related to energy expenditure
• Interactions with transient receptor potential vanilloid 1 (TRPV1) channels

6. Formulation Challenges and Innovations

Researchers are actively working on:

• Enhancing bioavailability through novel delivery systems
• Developing targeted formulations for specific applications
• Creating synergistic combinations with other bioactive compounds

7. Regulatory Considerations

Rutaecarpine (CAS 84-26-4) is primarily used in research settings. Its development for specific therapeutic applications would require comprehensive safety and efficacy evaluations to meet regulatory standards.

8. Future Research Directions

The scientific community anticipates:

• Advanced clinical trials for cardiovascular and metabolic disorders
• Exploration of Rutaecarpine’s potential in pain management therapies
• Investigation of its long-term effects on metabolic health

9. Collaborative Opportunities

We invite cardiologists, endocrinologists, pain specialists, and academic institutions to explore the research potential of Rutaecarpine. For inquiries, collaborations, or to discuss how this compound can benefit your research projects, please contact us at sales@nstchemicals.com.

Join us in advancing biomedical research with Rutaecarpine – a powerful alkaloid at the forefront of cardiovascular and metabolic research strategies.